TIPIN Antikörper (N-Term)
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- Target Alle TIPIN Antikörper anzeigen
- TIPIN (TIMELESS Interacting Protein (TIPIN))
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Bindungsspezifität
- AA 227-254, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TIPIN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TIPIN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-254 amino acids from the N-terminal region of human TIPIN.
- Klon
- RB40607
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product TIPIN Primärantikörper
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- Applikationshinweise
- WB: 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).
: "Human Timeless and Tipin stabilize replication forks and facilitate sister-chromatid cohesion." in: Journal of cell science, Vol. 123, Issue Pt 5, pp. 660-70, (2010) (PubMed).
: "Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors." in: Journal of molecular biology, Vol. 366, Issue 1, pp. 36-52, (2007) (PubMed).
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Tipin-replication protein A interaction mediates Chk1 phosphorylation by ATR in response to genotoxic stress." in: The Journal of biological chemistry, Vol. 285, Issue 22, pp. 16562-71, (2010) (PubMed).
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- Target
- TIPIN (TIMELESS Interacting Protein (TIPIN))
- Andere Bezeichnung
- TIPIN (TIPIN Produkte)
- Synonyme
- 1110005A05Rik antikoerper, 1110018P21Rik antikoerper, RGD1564084 antikoerper, MGC82649 antikoerper, zgc:91928 antikoerper, tipin antikoerper, TIMELESS interacting protein antikoerper, timeless interacting protein antikoerper, timeless interacting protein S homeolog antikoerper, timeless interacting protein L homeolog antikoerper, TIPIN antikoerper, Tipin antikoerper, tipin.S antikoerper, tipin antikoerper, tipin.L antikoerper
- Hintergrund
- Required for normal progression of S-phase. Important for cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light.
- Molekulargewicht
- 34555
- NCBI Accession
- NP_060328
- UniProt
- Q9BVW5
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