TRIM22 Antikörper (N-Term)

Produktnummer ABIN1881901

Produktdetails anti-TRIM22 Antikörper

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Bindungsspezifität: AA 67-96, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM22 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRIM22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-96 amino acids from the N-terminal region of human TRIM22.

Klon: RB33242

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-TRIM22 Antikörper (ABIN1881901)

Kajaste-Rudnitski, Pultrone, Marzetta, Ghezzi, Coradin, Vicenzi: "Restriction factors of retroviral replication: the example of Tripartite Motif (TRIM) protein 5 alpha and 22." in: Amino acids, Vol. 39, Issue 1, pp. 1-9, (2010) (PubMed).

Petersson, Lönnbro, Herr, Mörgelin, Gullberg, Drott: "The human IFN-inducible p53 target gene TRIM22 colocalizes with the centrosome independently of cell cycle phase." in: Experimental cell research, Vol. 316, Issue 4, pp. 568-79, (2010) (PubMed).

Ovsyannikova, Dhiman, Haralambieva, Vierkant, OByrne, Jacobson, Poland: "Rubella vaccine-induced cellular immunity: evidence of associations with polymorphisms in the Toll-like, vitamin A and D receptors, and innate immune response genes." in: Human genetics, Vol. 127, Issue 2, pp. 207-21, (2010) (PubMed).

Ovsyannikova, Haralambieva, Dhiman, OByrne, Pankratz, Jacobson, Poland: "Polymorphisms in the vitamin A receptor and innate immunity genes influence the antibody response to rubella vaccination." in: The Journal of infectious diseases, Vol. 201, Issue 2, pp. 207-13, (2009) (PubMed).

Gao, Duan, Xu, Xiong: "Tripartite motif-containing 22 inhibits the activity of hepatitis B virus core promoter, which is dependent on nuclear-located RING domain." in: Hepatology (Baltimore, Md.), Vol. 50, Issue 2, pp. 424-33, (2009) (PubMed).

Details zu TRIM22

Target: TRIM22 (Tripartite Motif Containing 22 (TRIM22))

Andere Bezeichnung: TRIM22 (TRIM22 Produkte)

Hintergrund: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.

Molekulargewicht: 56947

NCBI Accession: NP_001186502, NP_006065

UniProt: Q8IYM9