TSC1 Antikörper (pSer591)
(2 Referenzen)-
- Target Alle TSC1 Antikörper anzeigen
- TSC1 (Tuberous Sclerosis 1 (TSC1))
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Bindungsspezifität
- pSer591
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TSC1 Antikörper ist unkonjugiert
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Applikation
- Dot Blot (DB)
- Homologie
- Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This mouse TSC1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S591 of mouse TSC1.
- Klon
- RB41240
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product TSC1 Primärantikörper
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anti-Tuberous Sclerosis 1 (TSC1) (AA 550-650) antibody
TSC1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibodyTSC1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 3A2 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (C-Term) antibodyTSC1 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 836-1164) antibodyTSC1 Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 5A8 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) antibodyTSC1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 Reaktivität: Human ELISA, WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 401-430) antibodyTSC1 Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB11648 unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (AA 101-344) antibodyTSC1 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (pSer505) antibodyTSC1 Reaktivität: Human, Maus, Schaf ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Tuberous Sclerosis 1 (TSC1) (pSer1130) antibodyTSC1 Reaktivität: Maus DB Wirt: Kaninchen Polyclonal RB41227 unconjugated
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- Applikationshinweise
- DB: 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." in: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).
: "Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice." in: Cancer research, Vol. 70, Issue 21, pp. 8937-47, (2010) (PubMed).
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: "Modeling the transmission dynamics of HIV/AIDS epidemics: an introduction and a review." in: Journal of infection in developing countries, Vol. 4, Issue 10, pp. 597-608, (2010) (PubMed).
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- Target
- TSC1 (Tuberous Sclerosis 1 (TSC1))
- Andere Bezeichnung
- TSC1 (TSC1 Produkte)
- Hintergrund
- In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
- Molekulargewicht
- 128746
- NCBI Accession
- NP_075025
- UniProt
- Q9EP53
- Pathways
- RTK Signalweg, AMPK Signaling, Regulation of Cell Size, Tube Formation
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