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Tuberin Antikörper (pThr1373)

TSC2 Reaktivität: Ratte DB Wirt: Kaninchen Polyclonal RB41276 unconjugated
Produktnummer ABIN1881935
  • Target Alle Tuberin (TSC2) Antikörper anzeigen
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    Bindungsspezifität
    • 33
    • 21
    • 19
    • 19
    • 16
    • 16
    • 15
    • 15
    • 15
    • 13
    • 11
    • 10
    • 10
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr1373
    Reaktivität
    • 284
    • 186
    • 121
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Ratte
    Wirt
    • 375
    • 12
    Kaninchen
    Klonalität
    • 367
    • 20
    Polyklonal
    Konjugat
    • 136
    • 34
    • 33
    • 31
    • 24
    • 23
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 1
    Dieser Tuberin Antikörper ist unkonjugiert
    Applikation
    • 209
    • 174
    • 121
    • 81
    • 80
    • 60
    • 37
    • 31
    • 20
    • 12
    • 8
    • 7
    • 6
    • 5
    • 2
    Dot Blot (DB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This rat TSC2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T1373 of rat TSC2.
    Klon
    RB41276
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product TSC2 Primärantikörper
  • Applikationshinweise
    DB: 1:500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Larson, Liu, Stevens, Li, Li, Evers, Gao: "Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24987-98, (2010) (PubMed).

    Di Nardo, Kramvis, Cho, Sadowski, Meikle, Kwiatkowski, Sahin: "Tuberous sclerosis complex activity is required to control neuronal stress responses in an mTOR-dependent manner." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 18, pp. 5926-37, (2009) (PubMed).

    Shiono, Kobayashi, Takahashi, Sun, Abe, Zhang, Wang, Piao, Takagi, Mineki, Taka, Tada, Sonobe, Momose, Ueda, Hino: "The G1556S-type tuberin variant suppresses tumor formation in tuberous sclerosis 2 mutant (Eker) rats despite its deficiency in mTOR inhibition." in: Oncogene, Vol. 27, Issue 52, pp. 6690-7, (2008) (PubMed).

  • Target
    Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
    Andere Bezeichnung
    TSC2 (TSC2 Produkte)
    Synonyme
    TSC2 antikoerper, fc16b02 antikoerper, tuberin antikoerper, wu:fc16b02 antikoerper, LAM antikoerper, TSC4 antikoerper, Nafld antikoerper, Tcs2 antikoerper, Rc antikoerper, TSC complex subunit 2 antikoerper, tuberin antikoerper, hypothetical protein antikoerper, tuberous sclerosis 2 antikoerper, TSC2 antikoerper, LOC5569538 antikoerper, tsc2 antikoerper, PGTG_00159 antikoerper, Tsc2 antikoerper
    Hintergrund
    Acts as a tumor suppressor, may play a role in cell cycle regulation, acute phase response, and negative regulation of cell proliferation [RGD].
    Molekulargewicht
    201278
    NCBI Accession
    NP_036812
    UniProt
    P49816
    Pathways
    RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus
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