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Tuberin Antikörper (AA 1397-1426)

Name: Tuberin Antikörper (AA 1397-1426)
SKU: ABIN1881946
Price: 445.5 EUR
Availability: InStock

TSC2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB42388 unconjugated

TSC2 Antibody (Center /) (ABIN1881946 and ABIN2838963) western blot analysis in 293 cell line lysates (35 μg/lane). (Tuberin Antikörper (AA 1397-1426))

Immunohistochemical analysis of paraffin-embedded H. (Tuberin Antikörper (AA 1397-1426))

IHC (p)

2 Abbildungen

(3 Referenzen)

Produktnummer ABIN1881946

Datenblatt (PDF)

Target Alle Tuberin (TSC2) Antikörper anzeigen

Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))
Bindungsspezifität
33

21

19

19

16

16

15

15

15

13

11

10

10

8

8

8

7

7

7

7

7

7

7

7

7

7

7

6

6

6

6

5

5

4

4

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
AA 1397-1426
Reaktivität
283

186

122

8

5

2

2

1

1

1

1

1
Human
Wirt
375

12
Kaninchen
Passende Sekundärantikörper
Klonalität
367

20
Polyklonal
Konjugat
136

34

33

31

24

23

7

7

7

7

7

7

7

7

7

6

6

5

5

5

5

5

5

1
Dieser Tuberin Antikörper ist unkonjugiert
Applikation
209

173

122

81

80

60

37

30

20

12

8

7

6

5

2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This TSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1397-1426 amino acids from the Central region of human TSC2.

Klon

RB42388

Isotyp

Ig Fraction

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anti-Tuberous Sclerosis 2 (TSC2) (AA 1601-1750) antibody
TSC2 Reaktivität: Human, Maus, Ratte ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Tuberous Sclerosis 2 (TSC2) (AA 1776-1805) antibody
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TSC2 Reaktivität: Human DB, IF Wirt: Kaninchen Polyclonal RB11388 unconjugated

anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibody
TSC2 Reaktivität: Human, Maus, Ratte ELISA, WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Tuberous Sclerosis 2 (TSC2) (AA 900-1150) antibody
TSC2 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Tuberous Sclerosis 2 (TSC2) (AA 1396-1496) antibody
TSC2 Reaktivität: Human ELISA, WB, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Tuberous Sclerosis 2 (TSC2) (pThr927) antibody
TSC2 Reaktivität: Maus, Ratte ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Tuberous Sclerosis 2 (TSC2) (pThr1462) antibody
TSC2 Reaktivität: Human DB Wirt: Kaninchen Polyclonal RB13340 unconjugated

Applikationshinweise

WB: 1:1000. IHC-P: 1:25

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Dántola, Denofrio, Zurbano, Gimenez, Ogilby, Lorente, Thomas: "Mechanism of photooxidation of folic acid sensitized by unconjugated pterins." in: Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, Vol. 9, Issue 12, pp. 1604-12, (2010) (PubMed).

Larson, Liu, Stevens, Li, Li, Evers, Gao: "Tuberous sclerosis complex 2 (TSC2) regulates cell migration and polarity through activation of CDC42 and RAC1." in: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24987-98, (2010) (PubMed).

Liu, Wu, Chen, Ter-Minassian, Asomaning, Zhai, Wang, Su, Heist, Kulke, Lin, Liu, Christiani: "A Large-scale genetic association study of esophageal adenocarcinoma risk." in: Carcinogenesis, Vol. 31, Issue 7, pp. 1259-63, (2010) (PubMed).
Target

Tuberin (TSC2) (Tuberous Sclerosis 2 (TSC2))

Andere Bezeichnung

TSC2 (TSC2 Produkte)

Synonyme

TSC2 antikoerper, fc16b02 antikoerper, tuberin antikoerper, wu:fc16b02 antikoerper, LAM antikoerper, TSC4 antikoerper, Nafld antikoerper, Tcs2 antikoerper, Rc antikoerper, TSC complex subunit 2 antikoerper, tuberin antikoerper, hypothetical protein antikoerper, tuberous sclerosis 2 antikoerper, TSC2 antikoerper, LOC5569538 antikoerper, tsc2 antikoerper, PGTG_00159 antikoerper, Tsc2 antikoerper

Hintergrund

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht

200608

NCBI Accession

NP_000539, NP_001070651, NP_001107854

UniProt

P49815

Pathways

RTK Signalweg, AMPK Signaling, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus