TXN Antikörper (C-Term)
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- Target Alle TXN Antikörper anzeigen
- TXN (Thioredoxin (TXN))
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Bindungsspezifität
- AA 66-94, C-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TXN Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Homologie
- B, M, Pig, Rb, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This TXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the C-terminal region of human TXN.
- Klon
- RB42816
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product TXN Primärantikörper
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- Applikationshinweise
- WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 6 months
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Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity." in: Redox biology, Vol. 14, pp. 237-249, (2018) (PubMed).
: "
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Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity." in: Redox biology, Vol. 14, pp. 237-249, (2018) (PubMed).
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- Target
- TXN (Thioredoxin (TXN))
- Andere Bezeichnung
- TXN (TXN Produkte)
- Synonyme
- TRDX antikoerper, TRX antikoerper, TRX1 antikoerper, ADF antikoerper, AW550880 antikoerper, Trx1 antikoerper, Txn antikoerper, trx antikoerper, TXN antikoerper, SCM1.18 antikoerper, trxA3 antikoerper, thioredoxin antikoerper, TR-1 antikoerper, Trx-1 antikoerper, thioredoxin antikoerper, thioredoxin 1 antikoerper, thioredoxin L homeolog antikoerper, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) antikoerper, thioredoxin pseudogene antikoerper, cytosolic thioredoxin Trx1 antikoerper, TXN antikoerper, Txn1 antikoerper, txn.L antikoerper, txn antikoerper, trx antikoerper, SCO0885 antikoerper, PHG25ORF099c antikoerper, LOC100349046 antikoerper, Txn antikoerper, trx1 antikoerper
- Hintergrund
- Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. ADF augments the expression of the interleukin-2 receptor TAC (IL2R/P55).
- Molekulargewicht
- 11737
- NCBI Accession
- NP_001231867, NP_003320
- UniProt
- P10599
- Pathways
- Carbohydrate Homeostasis, Cell RedoxHomeostasis
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