UBE3C Antikörper (AA 549-578)

Produktnummer ABIN1881969

Produktdetails anti-UBE3C Antikörper

Target: UBE3C (Ubiquitin Protein Ligase E3C (UBE3C))

Bindungsspezifität: AA 549-578

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBE3C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This UBE3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 549-578 amino acids from the Central region of human UBE3C.

Klon: RB44044

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-UBE3C Antikörper (ABIN1881969)

Hillier, Fulton, Fulton, Graves, Pepin, Wagner-McPherson, Layman, Maas, Jaeger, Walker, Wylie, Sekhon, Becker, OLaughlin, Schaller, Fewell, Delehaunty, Miner, Nash, Cordes, Du, Sun, Edwards et al.: "The DNA sequence of human chromosome 7. ..." in: Nature, Vol. 424, Issue 6945, pp. 157-64, (2003) (PubMed).

Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: "Human chromosome 7: DNA sequence and biology. ..." in: Science (New York, N.Y.), Vol. 300, Issue 5620, pp. 767-72, (2003) (PubMed).

You, Pickart: "A HECT domain E3 enzyme assembles novel polyubiquitin chains." in: The Journal of biological chemistry, Vol. 276, Issue 23, pp. 19871-8, (2001) (PubMed).

Details zu UBE3C

Target: UBE3C (Ubiquitin Protein Ligase E3C (UBE3C))

Andere Bezeichnung: UBE3C (UBE3C Produkte)

Synonyme: UBE3C antikoerper, RGD1559986 antikoerper, zgc:63649 antikoerper, AI853514 antikoerper, mKIAA0010 antikoerper, HECTH2 antikoerper, kiaa0010 antikoerper, MGC146390 antikoerper, ubiquitin protein ligase E3C antikoerper, ubiquitin protein ligase E3C S homeolog antikoerper, UBE3C antikoerper, Ube3c antikoerper, ube3c antikoerper, ube3c.S antikoerper

Hintergrund: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'-or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.

Molekulargewicht: 123923

NCBI Accession: NP_055486

UniProt: Q15386