VANGL2 Antikörper (N-Term)

Produktnummer ABIN1881989

Produktdetails anti-VANGL2 Antikörper

Target: VANGL2 (Vang-Like 2 (VANGL2))

Bindungsspezifität: AA 37-65, N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VANGL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This VANGL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human VANGL2.

Klon: RB40615

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Details zu VANGL2

Target: VANGL2 (Vang-Like 2 (VANGL2))

Andere Bezeichnung: VANGL2 (VANGL2 Produkte)

Hintergrund: Planar cell polarity (PCP) is the term given to global cell polarization, such as the alignment of mammalian body hair along the anterior-posterior axis or the orientation of steriocilia bundles in the inner ear. VANGL2 is a PCP protein that is involved in the transmission of directional cues to align either individual cells within an epithelial sheet or multicellular clusters, which polarize as a group (Devenport and Fuchs, 2008 [PubMed 18849982]).

Molekulargewicht: 59714

NCBI Accession: NP_065068

UniProt: Q9ULK5

Pathways: WNT Signalweg, Stem Cell Maintenance, Tube Formation, Asymmetric Protein Localization