This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This ZNF43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-99 amino acids from the N-terminal region of human ZNF43.
ZNF43
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
WB: 1:1000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Haltbarkeit
6 months
Takahashi, Furuchi, Naganuma: "Endocytic Ark/Prk kinases play a critical role in adriamycin resistance in both yeast and mammalian cells." in: Cancer research, Vol. 66, Issue 24, pp. 11932-7, (2006) (PubMed).
Simpson, Wellenreuther, Poustka, Pepperkok, Wiemann: "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing." in: EMBO reports, Vol. 1, Issue 3, pp. 287-92, (2001) (PubMed).
Bellefroid, Marine, Ried, Lecocq, Rivière, Amemiya, Poncelet, Coulie, de Jong, Szpirer: "Clustered organization of homologous KRAB zinc-finger genes with enhanced expression in human T lymphoid cells." in: The EMBO journal, Vol. 12, Issue 4, pp. 1363-74, (1993) (PubMed).
Lovering, Trowsdale: "A gene encoding 22 highly related zinc fingers is expressed in lymphoid cell lines." in: Nucleic acids research, Vol. 19, Issue 11, pp. 2921-8, (1991) (PubMed).
Bellefroid, Poncelet, Lecocq, Revelant, Martial: "The evolutionarily conserved Krüppel-associated box domain defines a subfamily of eukaryotic multifingered proteins." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 9, pp. 3608-12, (1991) (PubMed).
This gene belongs to the C2H2-type zinc finger gene family. The zinc finger proteins are involved in gene regulation and development, and are quite conserved throughout evolution. Like this gene product, a third of the zinc finger proteins containing C2H2 fingers also contain the KRAB domain, which has been found to be involved in protein-protein interactions.