ABO Antikörper (N-Term)

Produktnummer ABIN1882200

Produktdetails anti-ABO Antikörper

Target: ABO (Histo-blood group A transferase (ABO))

Bindungsspezifität: AA 41-68, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ABO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.

Immunogen: This ABO antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human ABO.

Klon: 593CT3-2-2

Isotyp: IgM

Anwendungsinformationen

Applikationshinweise: WB: 1:200~6400

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Mouse monoclonal antibody supplied in crude ascites with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 6 months

Referenzen für anti-ABO Antikörper (ABIN1882200)

Thuresson, Chester, Storry, Olsson et al.: "ABO transcript levels in peripheral blood and erythropoietic culture show different allele-related patterns independent of the CBF/NF-Y enhancer motif and multiple novel allele-specific variations in..." in: Transfusion, Vol. 48, Issue 3, pp. 493-504, (2008) (PubMed).

Vasan, Schlesinger, Arrode: "T cell immune responses to HIV-1." in: Frontiers in bioscience : a journal and virtual library, Vol. 12, pp. 2330-43, (2006) (PubMed).

Twu, Hsieh, Yu: "Expression of the histo-blood group B gene predominates in AB-genotype cells." in: Transfusion, Vol. 46, Issue 11, pp. 1988-96, (2006) (PubMed).

Jenkins, ODonnell: "ABO blood group determines plasma von Willebrand factor levels: a biologic function after all?" in: Transfusion, Vol. 46, Issue 10, pp. 1836-44, (2006) (PubMed).

Roubinet, Despiau, Calafell, Jin, Bertranpetit, Saitou, Blancher, Bertanpetit: "Evolution of the O alleles of the human ABO blood group gene." in: Transfusion, Vol. 44, Issue 5, pp. 707-15, (2004) (PubMed).

Details zu ABO

Target: ABO (Histo-blood group A transferase (ABO))

Andere Bezeichnung: ABO (ABO Produkte)

Synonyme: A3GALNT antikoerper, A3GALT1 antikoerper, GTB antikoerper, NAGAT antikoerper, ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase antikoerper, ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase, transferase B, alpha 1-3-galactosyltransferase) antikoerper, ABO antikoerper, Abo antikoerper

Hintergrund: This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The 'O' blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.

Molekulargewicht: 40934

NCBI Accession: NP_065202

UniProt: P16442