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EGFR Antikörper (C-Term)

Name: EGFR Antikörper (C-Term)
SKU: ABIN1882237
Price: 467.5 EUR
Availability: InStock

EGFR Reaktivität: Human WB, IHC (p) Wirt: Maus Monoclonal 688CT33-1-3 unconjugated

All lanes : Anti-EGFR Antibody (C-term) at 1:8000 dilution Lane 1: A549 whole cell lysate Lane 2: PC-3 whole cell lysate Lane 3: A431 whole cell lysate Lane 4: MDA-MB-231 whole cell lysate Lysates/proteins at 20 μg per lane. (EGFR Antikörper (C-Term))

Immunohistochemical analysis of paraffin-embedded R. (EGFR Antikörper (C-Term))

IHC (p)

All lanes : Anti-EGFR Antibody (C-term) at 1:1000 dilution Lane 1: A431 whole cell lysate Lane 2: Hela whole cell lysate Lysates/proteins at 20 g per lane. (EGFR Antikörper (C-Term))

Immunohistochemical analysis of paraffin-embedded H. (EGFR Antikörper (C-Term))

IHC (p)

Immunohistochemical analysis of paraffin-embedded M. (EGFR Antikörper (C-Term))

IHC (p)

6 Abbildungen

Produktnummer ABIN1882237

Datenblatt (PDF)

Target Alle EGFR Antikörper anzeigen

EGFR (Epidermal Growth Factor Receptor (EGFR))
Bindungsspezifität
40

39

31

30

29

28

27

26

21

21

21

16

16

16

15

15

15

15

11

11

10

10

9

9

8

8

7

6

5

5

5

4

4

4

4

4

4

4

4

3

3

3

3

3

3

3

3

3

3

2
AA 1163-1191, C-Term
Reaktivität
756

296

287

26

26

24

20

14

8

3

2

2

1

1

1

1

1

1
Human
Wirt
581

176

14

13

5

1

1
Maus
Passende Sekundärantikörper
Klonalität
535

251

2
Monoklonal
Konjugat
416

58

29

22

20

17

17

16

15

15

15

12

10

10

10

10

10

10

10

10

10

8

8

5

4

4

4

4

4

2

1

1

1

1

1

1
Dieser EGFR Antikörper ist unkonjugiert
Applikation
539

248

152

152

131

102

102

94

82

49

37

35

34

19

11

7

6

4

4

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung

This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen

This EGFR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1163-1191 amino acids from the C-terminal region of human EGFR.

Klon

688CT33-1-3

Isotyp

IgG1

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Applikationshinweise

WB: 1:8000. WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25. IHC-P: 1:25

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Target

EGFR (Epidermal Growth Factor Receptor (EGFR))

Andere Bezeichnung

EGFR (EGFR Produkte)

Hintergrund

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.

Molekulargewicht

134277

NCBI Accession

NP_005219, NP_958439, NP_958440, NP_958441

UniProt

P00533

Pathways

NF-kappaB Signalweg, RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteine