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PCNA Antikörper (C-Term)

PCNA Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Maus Monoclonal 1157CT1-1-3 unconjugated
Produktnummer ABIN1882273
  • Target Alle PCNA Antikörper anzeigen
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Bindungsspezifität
    • 16
    • 16
    • 16
    • 15
    • 11
    • 11
    • 8
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 236-261, C-Term
    Reaktivität
    • 211
    • 152
    • 151
    • 54
    • 28
    • 27
    • 21
    • 19
    • 19
    • 18
    • 17
    • 15
    • 11
    • 10
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 130
    • 94
    • 3
    Maus
    Klonalität
    • 129
    • 97
    • 1
    Monoklonal
    Konjugat
    • 110
    • 17
    • 13
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PCNA Antikörper ist unkonjugiert
    Applikation
    • 189
    • 68
    • 64
    • 60
    • 53
    • 48
    • 45
    • 40
    • 30
    • 15
    • 15
    • 12
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Homologie
    B, Ha, Pr
    Aufreinigung
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    Immunogen
    This PCNA antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 236-261 amino acids from the C-terminal region of human PCNA.
    Klon
    1157CT1-1-3
    Isotyp
    IgG1
    Top Product
    Discover our top product PCNA Primärantikörper
  • Applikationshinweise
    WB: 1:2000. IHC: 1:2000. IHC-P: 1:25. IHC-P: 1:25
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Haltbarkeit
    6 months
  • Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: "The DNA sequence and comparative analysis of human chromosome 20. ..." in: Nature, Vol. 414, Issue 6866, pp. 865-71, (2002) (PubMed).

  • Target
    PCNA (Proliferating Cell Nuclear Antigen (PCNA))
    Andere Bezeichnung
    PCNA (PCNA Produkte)
    Hintergrund
    This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
    Molekulargewicht
    28769
    NCBI Accession
    NP_002583, NP_872590
    UniProt
    P12004
    Pathways
    Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie
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