FBXL20 Antikörper (C-Term)
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- Target Alle FBXL20 Antikörper anzeigen
- FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
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Bindungsspezifität
- C-Term
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FBXL20 Antikörper ist unkonjugiert
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Applikation
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- Aufreinigung
- Affinity chromatography purified via peptide column
- Immunogen
- 18 amino acid peptide near the carboxy terminus of the human SCRAPPER.
- Top Product
- Discover our top product FBXL20 Primärantikörper
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- PBS containing 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
- Handhabung
- Avoid freezing and thawing repeatly.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at 4 °C for short term use.Store at -20 °C for long term preservation.
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- Target
- FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
- Andere Bezeichnung
- SCRAPPER (FBXL20 Produkte)
- Synonyme
- Fbl2 antikoerper, Fbl20 antikoerper, fbl20 antikoerper, MGC81000 antikoerper, scrapper antikoerper, FBL2 antikoerper, 2610511F20Rik antikoerper, 4632423N09Rik antikoerper, AI849362 antikoerper, AL117906 antikoerper, C86145 antikoerper, Scr antikoerper, mKIAA4147 antikoerper, FBXL2 antikoerper, Fbxl2 antikoerper, F-box and leucine rich repeat protein 20 antikoerper, F-box and leucine-rich repeat protein 20 L homeolog antikoerper, F-box and leucine-rich repeat protein 20 antikoerper, F-box/LRR-repeat protein 20 antikoerper, putative fbxl20 antikoerper, F-box and leucine rich repeat protein 2 antikoerper, FBXL20 antikoerper, fbxl20.L antikoerper, LOAG_14232 antikoerper, LOC100080065 antikoerper, Smp_097020.1 antikoerper, FBXL2 antikoerper, Fbxl20 antikoerper
- Hintergrund
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Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif.SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases.Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane.Scrapper has orthologs in C.elegans, D.melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species.Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission.This identifies protein degradation as a mechanism for holding synaptic communication in check.
Synonyms: F-box, Leucine rich repeat protein 20, FBXL20, FBl2, FBL20 - NCBI Accession
- NP_116264
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