WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handhabung
Avoid freezing and thawing repeatly.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store at 4 °C for short term use.Store at -20 °C for long term preservation.
Target
DNAJC13
(DnaJ heat shock protein family (Hsp40) member C13 (DNAJC13))
RME8 antikoerper, D030002L11Rik antikoerper, Gm1124 antikoerper, RME-8 antikoerper, Rme8 antikoerper, mKIAA0678 antikoerper, DnaJ heat shock protein family (Hsp40) member C13 antikoerper, dnaJ homolog subfamily C member 13 antikoerper, DNAJC13 antikoerper, LOC100167963 antikoerper, LOC100640734 antikoerper, Dnajc13 antikoerper
Hintergrund
DNAJC13, also known as receptor-mediated endocytosis 8 (RME8), is the human homolog to a DnaJ domain-containing protein originally identified in a screen for endocytic defects in C.elegans.It is thought to be a co-chaperone of Hsc70 which regulates protein conformation at membrane sites and plays a role in intracellular trafficking, co-localizing with markers of the endosomal system.Recent experiments have indicated that the DNAJC13 protein is involved in membrane trafficking through early endosomes but not through degradative organelles.DNAJC13 has been also been shown to regulate the intracellular trafficking of the epidermal growth factor receptor. Synonyms: DNAJ homolog subfamily C member 13, receptor-mediated endocytosis 8, RME8