NPPB Antikörper (N-Term)

Produktnummer ABIN191916

Produktdetails anti-NPPB Antikörper

Target: NPPB (Natriuretic Peptides B (NPPB))

Bindungsspezifität: AA 1-21, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NPPB Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects Synthetic Human proBNP (aa 1-21), Human proBNP

Produktmerkmale: Synonyms: NPPB, Brain natriuretic peptide, BNP, proBNP, Gamma-brain natriuretic peptide

Aufreinigung: Protein A Chromatography

Immunogen: Synthetic human pro-BNP (aa 1-21) poly Lysin conjugatedAA Sequence: HPLGSPGSASDLETSGLQEQR

Klon: 21-06-06

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in aqua bidest to 1 mg/mL

Buffer: 200 mM Sodium Citrat / Tris, 500 mM NaCl buffer pH 7.5 containing 0.02 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Details zu NPPB

Target: NPPB (Natriuretic Peptides B (NPPB))

Andere Bezeichnung: Natriuretic Peptides B (NPPB Produkte)

Hintergrund: In cardiac tissue brain natriuretic peptide (BNP) is synthesized as 134 amino acid precursor (prepro-BNP), which is cleaved by proteases to form a 26 aa "signal" peptide and a 108 aa pro-BNP. Proteolytic digestion of pro-BNP results in formation of 76 aa amino-terminal NT-proBNP and biologically active 32 aa BNP hormone molecule. Both proBNP and NTproBNP circulate in human plasma and have been proposed as markers for early diagnosis of left ventricular dysfunction as well as prognostic markers of possible cardiac complications at patients with heart failure.Synonyms: BNP, Brain natriuretic peptide, Gamma-brain natriuretic peptide, NPPB, proBNP

Gen-ID: 4879

UniProt: P16860

Pathways: Hormone Activity