Laminin 5 Antikörper

Produktnummer ABIN191945

Produktdetails anti-Laminin 5 Antikörper

Target: Laminin 5 (LN-5)

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Laminin 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)

Produktmerkmale: Synonyms: Laminin-5

Aufreinigung: Protein A Chromatography

Immunogen: Human Laminin 5 beta 3 chain

Klon: 6F12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot. ELISA (coating antibody in Sandwich ELISA). Immunohistochemistry on Cryosections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Restore in aqua bidest to initial volume.

Buffer: PBS, pH 7.4

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Haltbarkeit: 12 months

Referenzen für anti-Laminin 5 Antikörper (ABIN191945)

Drumea-Mirancea, Wessels, Müller, Essl, Eble, Tolosa, Koch, Reinhardt, Sixt, Sorokin, Stierhof, Schwarz, Klein: "Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules." in: Journal of cell science, Vol. 119, Issue Pt 7, pp. 1396-405, (2006) (PubMed).

Amano, Akutsu, Ogura, Nishiyama: "Increase of laminin 5 synthesis in human keratinocytes by acute wound fluid, inflammatory cytokines and growth factors, and lysophospholipids." in: The British journal of dermatology, Vol. 151, Issue 5, pp. 961-70, (2004) (PubMed).

Sasaki, Amano, Nishiyama, Nakayama, Burgeson, Nakajima: "Expression of laminin 5, and collagen IV and VII in bullous pemphigoid skin." in: Archives of dermatological research, Vol. 290, Issue 5, pp. 283-5, (1998) (PubMed).

Barnstable, Bodmer, Brown, Galfre, Milstein, Williams, Ziegler: "Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis." in: Cell, Vol. 14, Issue 1, pp. 9-20, (1978) (PubMed).

Details zu Laminin 5

Target: Laminin 5 (LN-5)

Andere Bezeichnung: Laminin 5 (LN-5 Produkte)

Hintergrund: Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. laminin 5 is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: Laminin-5