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Laminin 5 Antikörper

LN-5 Reaktivität: Human, Ratte WB, IHC (fro), EIA Wirt: Maus Monoclonal 6F12 unconjugated
Produktnummer ABIN191945
  • Target Alle Laminin 5 (LN-5) Produkte
    Laminin 5 (LN-5)
    Reaktivität
    • 9
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 5
    • 4
    Maus
    Klonalität
    • 5
    • 4
    Monoklonal
    Konjugat
    • 9
    Dieser Laminin 5 Antikörper ist unkonjugiert
    Applikation
    • 8
    • 6
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA)
    Produktmerkmale
    Synonyms: Laminin-5
    Aufreinigung
    Protein A Chromatography
    Immunogen
    Human Laminin 5 beta 3 chain
    Klon
    6F12
    Isotyp
    IgG
  • Applikationshinweise
    Western blot. ELISA (coating antibody in Sandwich ELISA). Immunohistochemistry on Cryosections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Rekonstitution
    Restore in aqua bidest to initial volume.
    Buffer
    PBS, pH 7.4
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
    Shelf life: One year from despatch.
    Haltbarkeit
    12 months
  • Drumea-Mirancea, Wessels, Müller, Essl, Eble, Tolosa, Koch, Reinhardt, Sixt, Sorokin, Stierhof, Schwarz, Klein: "Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules." in: Journal of cell science, Vol. 119, Issue Pt 7, pp. 1396-405, (2006) (PubMed).

    Amano, Akutsu, Ogura, Nishiyama: "Increase of laminin 5 synthesis in human keratinocytes by acute wound fluid, inflammatory cytokines and growth factors, and lysophospholipids." in: The British journal of dermatology, Vol. 151, Issue 5, pp. 961-70, (2004) (PubMed).

    Sasaki, Amano, Nishiyama, Nakayama, Burgeson, Nakajima: "Expression of laminin 5, and collagen IV and VII in bullous pemphigoid skin." in: Archives of dermatological research, Vol. 290, Issue 5, pp. 283-5, (1998) (PubMed).

    Barnstable, Bodmer, Brown, Galfre, Milstein, Williams, Ziegler: "Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis." in: Cell, Vol. 14, Issue 1, pp. 9-20, (1978) (PubMed).

  • Target
    Laminin 5 (LN-5)
    Andere Bezeichnung
    Laminin 5 (LN-5 Produkte)
    Hintergrund
    Laminins are basement membrane components thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. laminin 5 is a complex glycoprotein composed of three subunits (alpha, beta, and gamma). Laminin 5 is thought to be involved in cell adhesion, signal transduction and differentiation of keratinocytes. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa. Alternatively spliced transcript variants encoding different isoforms have been identified.Synonyms: Laminin-5
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