This antibody detects Human beta-Defensin 4 (aa 3-39). There was cross reactivity obtained with Human beta-Defensin 1, beta-Defensin 2 and beta-Defensin 3.
ELISA. RIA. Western blot. Immunohistochemistry (paraffin sections kidney 1 μg/mL). Immunohistochemistry on frozen sections. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Rekonstitution
Restore in aqua bidest to 1 mg/mL.
Buffer
50 mM TRIS pH 7,4
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store lyophilized at 2 - 8 °C and reconstituted at -20 °C. Avoid repeated freezing andthawing. Shelf life: One year from despatch.
Beta 4 Defensin has antimicrobial activity and synergistic effects with lysozyme and DEFB103. High expression levels are seen in the testis. Gastric antrum also exhibits relativey high levels. A lower exppression is observed in uterus and neutrophils thyroid gland, lung, and kidney. No detectable expression was observed in other tissues tested. Antimicrobial activity is decreased when the sodium chloride concentration is increased. Beta 4 Defensin belongs to the beta-defensin family.Synonyms: BD-4, Beta-defensin 4, DEFB-4, DEFB104, DEFB104A, DEFB104B, DEFB4, hBD-4