Ezrin Antikörper (Tyr353)
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- Target Alle Ezrin (EZR) Antikörper anzeigen
- Ezrin (EZR)
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Bindungsspezifität
- Tyr353
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Ezrin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- Ezrin antibody detects endogenous levels of total Ezrin protein.
- Aufreinigung
- Affinity-chromatography using epitope-specific immunogen
- Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from human Ezrin around the phosphorylation site of tyrosine 353 (Q-D-YP-E-E).
- Top Product
- Discover our top product EZR Primärantikörper
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- Applikationshinweise
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Western Blot: 1: 500approx. 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS(without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
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- Target
- Ezrin (EZR)
- Andere Bezeichnung
- Ezrin (EZR Produkte)
- Hintergrund
- Ezrin (also known as p81, 80K, or cytovillin) is a cytoplasmic protein which is enriched in microvilli and other cell surface structures. Its NH2-terminal domain is associated with the plasma membrane and the COOH-terminal domain with the cytoskeleton. Ezrin has an actin-binding capability. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas. Ezrin serves as a tyrosine kinase substrate, and is phosphorylated in EGF-stimulated cells.Synonyms: Cytovillin, EZR, VIL2, Villin-2, p81
- Gen-ID
- 7430
- NCBI Accession
- NP_001104547
- UniProt
- P15311
- Pathways
- Maintenance of Protein Location
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