Cortactin Antikörper (Tyr421)
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- Target Alle Cortactin (CTTN) Antikörper anzeigen
- Cortactin (CTTN)
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Bindungsspezifität
- Tyr421
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Reaktivität
- Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cortactin Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- The antiserum was produced against synthesized non-phosphopeptide derived from mouse Cortactin around the phosphorylation site of tyrosine 421 (P-I-YP-E-D).
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- Discover our top product CTTN Primärantikörper
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anti-Cortactin (CTTN) (N-Term) antibody
KO Validated CTTN Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 214-513) antibodyCTTN Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) antibodyCTTN Reaktivität: Human WB, IHC, IF, IP Wirt: Kaninchen Monoclonal unconjugated
anti-Cortactin (CTTN) (AA 341-450) antibodyCTTN Reaktivität: Human WB, ELISA, PLA Wirt: Maus Monoclonal 2B5 unconjugated
anti-Cortactin (CTTN) antibodyCTTN Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 4C6 unconjugated
anti-Cortactin (CTTN) (pTyr466) antibodyCTTN Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 1-509) antibodyCTTN Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 1-509) antibodyCTTN Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Cortactin (CTTN) (AA 273-302) antibodyCTTN Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB33698 unconjugated
anti-Cortactin (CTTN) (pTyr421) antibodyCTTN Reaktivität: Human, Maus, Ratte WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
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Immunohistochemistry: 1: 50-1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
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- Target
- Cortactin (CTTN)
- Andere Bezeichnung
- Cortactin (CTTN Produkte)
- Hintergrund
- Cortactin is an 80/85 kDa cytoskeleton protein that facilitates assembly of cortical actin. Cortactin is widely expressed in most adherent cells and is a prominent substrate of protein tyrosine kinase Src in vivo and in vitro. The protein sequence of cortactin contains multiple amino terminal tandem repeats of a unique 37 amino acid sequence, which associates with actin, and a Src homology 3 (SH3) domain at the carboxyl terminus. Between the repeat and the SH3 domain, there is an alpha helical structure followed by a proline rich region. Between the proline rich region and the SH3 domain, there are a series of Src phosphorylation sites (Tyr421, Tyr470, and Tyr486). In vitro, cortactin binds to and cross links F actin into meshworks.Synonyms: Amplaxin, CTTN, EMS1, Oncogene EMS1
- Gen-ID
- 10090
- UniProt
- Q60598
- Pathways
- MAPK Signalweg
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