CD300E Antikörper

Produktnummer ABIN1981868

Produktdetails anti-CD300E Antikörper

Target: CD300E (CD300e Molecule (CD300E))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD300E Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Spezifität: The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.

Kreuzreaktivität (Details): Human

Aufreinigung: Purified by protein-A affinity chromatography.

Reinheit: > 95 % (by SDS-PAGE)

Immunogen: CD300e-HA-transfected cells

Klon: UP-H2

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Recommended dilution: 1-4 μg/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze. Do not use after expiration date stamped on vial label.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2-8°C. Do not freeze.

Referenzen für anti-CD300E Antikörper (ABIN1981868)

Brckalo, Calzetti, Pérez-Cabezas, Borrs, Cassatella, López-Botet: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." in: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).

Details zu CD300E

Target: CD300E (CD300e Molecule (CD300E))

Andere Bezeichnung: CD300e (CD300E Produkte)

Synonyme: BC034097 antikoerper, CLM2 antikoerper, Cd300le antikoerper, TREM5 antikoerper, CD300LE antikoerper, CLM-2 antikoerper, CMRF35-A5 antikoerper, IREM-2 antikoerper, IREM2 antikoerper, PIgR-2 antikoerper, PIgR2 antikoerper, CD300E molecule antikoerper, CD300e molecule antikoerper, Cd300e antikoerper, CD300E antikoerper

Hintergrund: CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2

Gen-ID: 342510

UniProt: Q496F6