LRRC32 Antikörper
(1 reference)-
- Target Alle LRRC32 Antikörper anzeigen
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LRRC32 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Spezifität
- The mouse monoclonal antibody GARP5 recognizes GARP / LRRC32, an approximately 80 kDa glycoprotein expressed e.g. on the surface of megakaryocytes, platelets and activated Treg cells.
- Kreuzreaktivität (Details)
- Human
- Aufreinigung
- Purified by protein-A affinity chromatography.
- Reinheit
- > 95 % (by SDS-PAGE)
- Immunogen
- Purified human sGARP protein
- Klon
- GARP5
- Isotyp
- IgG1
- Top Product
- Discover our top product LRRC32 Primärantikörper
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anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 162-405) antibody
LRRC32 Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 234-260) antibodyLRRC32 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB18218 unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 234-260) antibodyLRRC32 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 400-643) antibodyLRRC32 Reaktivität: Maus WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 250-300) antibodyLRRC32 Reaktivität: Human, Maus, Ratte, Affe WB, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 301-500) antibodyLRRC32 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 20-627) antibody (FITC)LRRC32 Reaktivität: Human, Maus FACS Wirt: Maus Monoclonal Plato-1 FITC
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 20-627) antibody (PE)LRRC32 Reaktivität: Human, Maus FACS Wirt: Maus Monoclonal Plato-1 PE
anti-Leucine Rich Repeat Containing 32 (LRRC32) antibody (Alexa Fluor 647)LRRC32 Reaktivität: Maus FACS Wirt: Ratte Monoclonal F011-5 Alexa Fluor 647
anti-Leucine Rich Repeat Containing 32 (LRRC32) (AA 23-612) antibodyLRRC32 Reaktivität: Human WB Wirt: Maus Monoclonal 50G10 unconjugated
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- Applikationshinweise
- Western blotting: Recommended dilution: 1-2 μg/mL, positive control: human thrombocytes, reducing conditions
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Do not freeze. Do not use after expiration date stamped on vial label.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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-
: "GARP regulates the bioavailability and activation of TGF?." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1129-39, (2012) (PubMed).
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: "GARP regulates the bioavailability and activation of TGF?." in: Molecular biology of the cell, Vol. 23, Issue 6, pp. 1129-39, (2012) (PubMed).
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- Target
- LRRC32 (Leucine Rich Repeat Containing 32 (LRRC32))
- Andere Bezeichnung
- GARP / LRRC32 (LRRC32 Produkte)
- Hintergrund
- Leucine rich repeat containing 32,GARP (glycoprotein A repetitions predominant protein), also known as garpin or LRRC32 (leucin-rich repeat containing protein 32) is an approximately 80 kDa transmembrane glycoprotein detected on the surface of megakaryocytes, platelets, and activated Treg cells. It binds to the latency-associated peptide (LAP) domain of pro-TGF beta and regulates its storage and activation. The expression of GARP on Treg cells seems to be necessary for their suppressive functions.,GARP, D11S833E
- Gen-ID
- 2615
- UniProt
- Q14392
- Pathways
- Activated T Cell Proliferation
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