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CD300E Antikörper (APC)

CD300E Reaktivität: Human FACS Wirt: Maus Monoclonal UP-H2 APC
Produktnummer ABIN1981879
  • Target Alle CD300E Antikörper anzeigen
    CD300E (CD300e Molecule (CD300E))
    Reaktivität
    • 34
    • 8
    Human
    Wirt
    • 22
    • 12
    Maus
    Klonalität
    • 23
    • 11
    Monoklonal
    Konjugat
    • 9
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD300E Antikörper ist konjugiert mit APC
    Applikation
    • 20
    • 14
    • 11
    • 5
    • 4
    • 3
    • 1
    Flow Cytometry (FACS)
    Spezifität
    The mouse monoclonal antibody UP-H2 recognizes an extracellular epitope on CD300e / IREM-2, a 32 kDa glycoprotein expressed by mature monocytes and peripheral blood myeloid dendritic cells.
    Kreuzreaktivität (Details)
    Human
    Aufreinigung
    Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogen
    CD300e-HA-transfected cells
    Klon
    UP-H2
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD300E Primärantikörper
  • Applikationshinweise
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Kommentare

    The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Do not freeze. Avoid prolonged exposure to light.
    Do not use after expiration date stamped on vial label.
    Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Brckalo, Calzetti, Pérez-Cabezas, Borrs, Cassatella, López-Botet: "Functional analysis of the CD300e receptor in human monocytes and myeloid dendritic cells." in: European journal of immunology, Vol. 40, Issue 3, pp. 722-32, (2010) (PubMed).

    Aguilar, Alvarez-Errico, García-Montero, Orfao, Sayós, López-Botet: "Molecular characterization of a novel immune receptor restricted to the monocytic lineage." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 11, pp. 6703-11, (2004) (PubMed).

  • Target
    CD300E (CD300e Molecule (CD300E))
    Andere Bezeichnung
    CD300e (CD300E Produkte)
    Synonyme
    BC034097 antikoerper, CLM2 antikoerper, Cd300le antikoerper, TREM5 antikoerper, CD300LE antikoerper, CLM-2 antikoerper, CMRF35-A5 antikoerper, IREM-2 antikoerper, IREM2 antikoerper, PIgR-2 antikoerper, PIgR2 antikoerper, CD300E molecule antikoerper, CD300e molecule antikoerper, Cd300e antikoerper, CD300E antikoerper
    Hintergrund
    CD300e molecule,CD300e / IREM-2 (immune receptor expressed by myeloid cells 2), also known as CLM2 or LMIR6, is a monomeric transmembrane glycoprotein with a single extracellular immunoglobulin-like domain. Intracellularly it associates with DAP-12, an ITAM-containing adaptor molecule. CD300e is expressed on mature monocytes and peripheral blood myeloid dendritic cells. Its crosslinking leads to release of pro-inflammatory cytokines, and increased expression of activation markers.,CLM2, CMRF35-A5, LMIR6, IREM-2, PlgR2
    Gen-ID
    342510
    UniProt
    Q496F6
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