This product contains ProClinTM: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Handhabung
Avoid repeated freeze. Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Lagerung
-20 °C/-80 °C
Informationen zur Lagerung
Upon delivery aliquot and store at -20 °C or -80 °C.
Target
Phosphoprotein
Synonyme
P antikoerper, Protein P antikoerper, subunit of RNA dependent RNA polymerase (RdRp); chaperone for Measles virus nucleocapsid protein antikoerper, P/V/C antikoerper
Substanzklasse
Viral Protein
Hintergrund
Non catalytic polymerase cofactor and regulatory protein that plays a role in viral transcription and replication. Stabilizes the RNA polymerase L to the N-RNA template and binds the soluble protein N, preventing it from encapsidating non-genomic RNA. Also inhibits host IFN-alpha and IFN-beta signaling by binding and retaining phosphorylated STAT1 in the cytoplasm or by inhibiting the DNA binding of STAT1 in the nucleus. Might be involved, through interaction with host dynein, in intracellular microtubule-dependent virus transport of incoming virus from the synapse toward the cell body Synonyms: Protein M1 P