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BRCA2 Antikörper (AA 2480-2530)

BRCA2 Reaktivität: Human Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2017604
  • Target Alle BRCA2 Antikörper anzeigen
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Bindungsspezifität
    • 12
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2480-2530
    Reaktivität
    • 43
    • 23
    • 20
    • 4
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 42
    • 7
    Kaninchen
    Klonalität
    • 41
    • 8
    Polyklonal
    Konjugat
    • 32
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser BRCA2 Antikörper ist unkonjugiert
    Applikation
    Bitte anfragen
    Spezifität
    BRCA2 Antibody detects endogenous levels of human and mouse BRCA2.
    Kreuzreaktivität
    Maus
    Produktmerkmale
    BRCA2 Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 2480-2530 of human BRCA2 (Swiss Prot: P51587).
    Aufreinigung
    Immunoaffinity chromatography.
    Immunogen
    KLH-coupled synthetic peptide within residues 2480-2530 of human BRCA2
    Isotyp
    IgG
    Top Product
    Discover our top product BRCA2 Primärantikörper
  • Kommentare

    Positive Control: HEK293 and Mouse brain

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
    Konzentration
    0.5 mg/mL
    Buffer
    Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
  • Target
    BRCA2 (Breast Cancer 2, Early Onset (BRCA2))
    Andere Bezeichnung
    BRCA2 (BRCA2 Produkte)
    Synonyme
    BRCC2 antikoerper, BROVCA2 antikoerper, FACD antikoerper, FAD antikoerper, FAD1 antikoerper, FANCB antikoerper, FANCD antikoerper, FANCD1 antikoerper, GLM3 antikoerper, PNCA2 antikoerper, 30169 antikoerper, BcDNA:SD25109 antikoerper, CG13583 antikoerper, CG13584 antikoerper, CG30169 antikoerper, Dmel\\CG30169 antikoerper, brca2 antikoerper, dmbrca2 antikoerper, fancd1 antikoerper, BRCA2 antikoerper, brcc2 antikoerper, brovca2 antikoerper, facd antikoerper, fad antikoerper, fad1 antikoerper, fancb antikoerper, AI256696 antikoerper, AW045498 antikoerper, Fancd1 antikoerper, RAB163 antikoerper, BRCA2, DNA repair associated antikoerper, Breast cancer 2, early onset homolog antikoerper, breast cancer 2, early onset antikoerper, BRCA2 antikoerper, Brca2 antikoerper, brca2 antikoerper, LOC584780 antikoerper
    Hintergrund
    Breast cancer type 2 susceptibility protein (BRCA2) is involved in double-strand break repair and/or homologous recombination. It may participate in S phase checkpoint activation. In addition, It interacts with RAD51 and DSS1 and binds to ubiquitinated FANCD2. It also interacts with PALB2, enabling the recombinational repair and checkpoints functions. Defects in BRCA2 can cause genetic susceptibility to breast cancer (BC), also called susceptibility to familial breast-ovarian cancer type 2 (BROVCA2).
    Molekulargewicht
    Predicted Band Size: 390 KD
    Observed Band Size: 390 KD
    UniProt
    P51587
    Pathways
    DNA Reparatur, M Phase, Maintenance of Protein Location
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