GLRA1 Antikörper (N-Term)

Produktnummer ABIN2017608

Produktdetails anti-GLRA1 Antikörper

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLRA1 Antikörper ist unkonjugiert

Applikation: Bitte anfragen

Spezifität: Alpha 1 Glycine Receptor Antibody, pAb, Rabbit detects endogenous levels of mouse alpha 1 Glycine Receptor.

Kreuzreaktivität: Maus

Kreuzreaktivität (Details): It is predicted to react with human alpha 1 Glycine Receptor according to sequence homology.
Reactivity to other species is not tested yet.

Produktmerkmale: alpha 1 Glycine Receptor Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor (Swiss Prot: P23415).

Aufreinigung: Immunoaffinity chromatography

Immunogen: KLH-coupled synthetic peptide from N-terminal of human alpha 1 Glycine Receptor

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Positive Control: Mouse brain

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.

Konzentration: 0.5 mg/mL

Buffer: Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.

Details zu GLRA1

Target: GLRA1 (Glycine Receptor, alpha 1 (GLRA1))

Abstract: GLRA1 Produkte

Synonyme: GLYRA1 antikoerper, HKPX1 antikoerper, STHE antikoerper, [a]Z1 antikoerper, B230397M16Rik antikoerper, nmf11 antikoerper, oscillator antikoerper, ot antikoerper, spasmodic antikoerper, spd antikoerper, glycine receptor alpha 1 antikoerper, glycine receptor, alpha 1 antikoerper, glycine receptor, alpha 1 subunit antikoerper, GLRA1 antikoerper, Glra1 antikoerper, glra1 antikoerper

Hintergrund: The glycine receptor is a neurotransmitter-gated ion channel. Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Binding of glycine to its receptor increases the chloride conductance and thus produces hyperpolarization. The alpha-1 subunit of the glycine receptor is a ligand-gated chloride channel. This inhibitory glycine receptor mediates postsynaptic inhibition in the spinal cord and other regions of the central nervous system. It is a pentameric receptor composed of alpha and beta subunits. Defects in alpha 1 Glycine Receptor are implicated in the pathophysiology of startle disease (STHE).

Molekulargewicht: Predicted Band Size: 52 KD
Observed Band Size: 48 KD

UniProt: P23415

Pathways: Synaptic Membrane