ROCK1 Antikörper (AA 1114-1126)

Produktnummer ABIN207918

Produktdetails anti-ROCK1 Antikörper

Target: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Bindungsspezifität: AA 1114-1126

Reaktivität: Human, Maus, Ratte, Affe, Rind (Kuh), Fledermaus, Hund, Pferd

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ROCK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This mAb recognizes the cleaved C-terminus of ROCK-1. It does not recognize the full-length protein. Since ROCK-1 is cleaved by caspase-3 during apoptosis, this may be used for detection of apoptosis.

Homologie: Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Bovine, Dog, Bat, Horse, Opossum, Platypus (100%) Rabbit (92%) Chicken (85%).

Aufreinigung: Protein G purified

Immunogen: This antibody was generated by immunizing mice with a synthetic peptide sequence corresponding to residues 1114-1126 GNLPESRIEGWLS of human ROCK-1. Immunogen peptide sequence is adjacent to the caspase-3 cleavage site of ROCK-1. Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Bovine, Dog, Bat, Horse, Opossum, Platypus (100%), Rabbit (92%), Chicken (85%).

Type of Immunogen: Synthetic peptide

Klon: 154C1465

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Approved: WB (1 - 2 μg/mL)

Not recommended for: IHC-P

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.2 % gelatin, 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu ROCK1

Target: ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))

Andere Bezeichnung: Rho Kinase / ROCK1 (ROCK1 Produkte)

Synonyme: LOC100229794 antikoerper, CG9774 antikoerper, DROK antikoerper, DRhk antikoerper, DRok antikoerper, Dmel\\CG9774 antikoerper, Drok antikoerper, ROCK antikoerper, ROCK-1 antikoerper, ROCK1 antikoerper, ROK antikoerper, ROKalpha/beta antikoerper, Rhk antikoerper, RhoK antikoerper, Rock antikoerper, Rok antikoerper, dROK antikoerper, dRok antikoerper, drok antikoerper, 1110055K06Rik antikoerper, Rock-I antikoerper, P160Rock antikoerper, ROCK-I antikoerper, P160ROCK antikoerper, p160ROCK antikoerper, Rho associated coiled-coil containing protein kinase 1 antikoerper, Rho kinase antikoerper, Rho-associated coiled-coil containing protein kinase 1 antikoerper, Rho-associated, coiled-coil containing protein kinase 1 antikoerper, ROCK1 antikoerper, Rok antikoerper, Rock1 antikoerper, rock1 antikoerper

Hintergrund: Name/Gene ID: ROCK1
Subfamily: ROCK
Family: Protein Kinase

Synonyms: ROCK1, p160 Rho-associated kinase, p160ROCK, p160 ROCK-1, p160-ROCK, p160RhoK, Rho-associated kinase, RockI, Rok, Rok alpha, Rho-alpha kinase, p160 rho-kinase, Rho kinase, ROCK-I, Rokalpha

Gen-ID: 6093

UniProt: Q13464

Pathways: Microtubule Dynamics, WNT Signalweg, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling