KIR2DL2 Antikörper (Extracellular Domain)

Produktnummer ABIN211120

Produktdetails anti-KIR2DL2 Antikörper

Target: KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))

Bindungsspezifität: Extracellular Domain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser KIR2DL2 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunoprecipitation (IP)

Spezifität: Recognizes the human CD158b cell surface antigen, a 58kD glycoprotein expressed by a subset of NK cells (also known as p58.2 antigen). This antibody also recognizes a 50kD molecule, which is highly homologous to p58.2 in the extracellular domain, but has a shorter cytoplasmic tail. Both molecules are members of the newly described natural killer cell receptor family. CD158b functions as a receptor specific for HLA Class I molecules, including Cw3 and related HLA-C alleles. This antibody can restore the lysis by human NK clones of otherwise lysis protected targets expressing Cw3.

Aufreinigung: Purified

Immunogen: NK cell clone E57.

Type of Immunogen: Cells

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo (1:10 - 1:50), IP

Usage: Suitable for use in Flow Cytometry and Immunoprecipitation. Flow Cytometry: 1:10-1:50. Use 10 μL to label 1 x10⁶ in 100 μL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.2, 0.5 % BSA, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu KIR2DL2

Target: KIR2DL2 (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 2 (KIR2DL2))

Andere Bezeichnung: KIR2DL2 / CD158b (KIR2DL2 Produkte)

Synonyme: NKAT6 antikoerper, p58.2 antikoerper, CD158b antikoerper, CD158B1 antikoerper, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 2 antikoerper, KIR2DL2 antikoerper

Hintergrund: Name/Gene ID: KIR2DL2
Family: Immunoglobulin

Synonyms: KIR2DL2, CD158B1, Cl-43, CD158k, MHC class I NK cell receptor, NKAT6, NKAT-6, p58 NK receptor CL-43, p58.2, CD158b, CD158b1 antigen

Gen-ID: 3803

UniProt: P43627