PDE11A Antikörper (Internal Region)

Produktnummer ABIN213553

Produktdetails anti-PDE11A Antikörper

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Bindungsspezifität: Internal Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Zebrafisch (Danio rerio), Fledermaus, Affe, Schwein, Huhn, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE11A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human PDE11A. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PDE6B (53 % ).

Homologie: Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Bat, Hamster, Elephant, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Pufferfish, Zebrafish (100%) Platypus, Xenopus, Stickleback (94%) Dog (88%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic 17 amino acid peptide from internal region of human PDE11A. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Bat, Hamster, Elephant, Horse, Rabbit, Pig, Opossum, Turkey, Chicken, Pufferfish, Zebrafish (100%), Platypus, Xenopus, Stickleback (94%), Dog (88%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, less than 0.1 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PDE11A

Target: PDE11A (phosphodiesterase 11A (PDE11A))

Andere Bezeichnung: PDE11A (PDE11A Produkte)

Synonyme: PPNAD2 antikoerper, 6330414F14Rik antikoerper, A630086N24Rik antikoerper, Gm350 antikoerper, PDE11A1 antikoerper, si:ch211-222f23.5 antikoerper, PDE11A antikoerper, ppnad2 antikoerper, Pde11a antikoerper, phosphodiesterase 11A antikoerper, phosphodiesterase 11a antikoerper, dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A antikoerper, PDE11A antikoerper, Pde11a antikoerper, pde11a antikoerper, LOC100470038 antikoerper

Hintergrund: Name/Gene ID: PDE11A
Subfamily: PDE - cAMP/cGMP dual-specific
Family: Phosphodiesterase

Synonyms: PDE11A, Pde11, PDE11A4, PDE11A1, PPNAD2, PDE11A2, PDE11A3, Phosphodiesterase 11A

Gen-ID: 50940

Pathways: cAMP Metabolic Process