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FAT4 Antikörper (AA 4351-4450) (Biotin)

FAT4 Reaktivität: Maus, Ratte ELISA, WB, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN2172808
  • Target Alle FAT4 Antikörper anzeigen
    FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
    Bindungsspezifität
    • 14
    • 5
    • 2
    • 1
    AA 4351-4450
    Reaktivität
    • 18
    • 14
    • 14
    Maus, Ratte
    Wirt
    • 29
    • 3
    Kaninchen
    Klonalität
    • 29
    • 3
    Polyklonal
    Konjugat
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FAT4 Antikörper ist konjugiert mit Biotin
    Applikation
    • 20
    • 13
    • 13
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDHF14
    Isotyp
    IgG
    Top Product
    Discover our top product FAT4 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    FAT4 (FAT Tumor Suppressor Homolog 4 (FAT4))
    Andere Bezeichnung
    CDHF14 (FAT4 Produkte)
    Synonyme
    CDHF14 antikoerper, CDHR11 antikoerper, FAT-J antikoerper, FATJ antikoerper, NBLA00548 antikoerper, 6030410K14Rik antikoerper, 9430004M15 antikoerper, FAT atypical cadherin 4 antikoerper, FAT4 antikoerper, Fat4 antikoerper
    Hintergrund

    Synonyms: Cadherin family member 14, CDHF14, FAT tumor suppressor homolog 4, Fat-like cadherin protein FAT-J, FAT4, FAT4_HUMAN, FATJ, hFat4, Nbla00548, Protocadherin Fat 4.

    Background: The cadherins represent a family of Ca2+-dependent adhesion molecules that function to mediate cell to cell binding that is critical for the maintenance of structure and morphogenesis. Cadherins contain a large extracellular domain at the N-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short C-terminal intracellular domain interacts with a variety of cytoplasmic proteins, including beta-catenin, to regulate cadherin function. The cadherin superfamily includes cadherins, protocadherins, desmogleins and desmocollins. FAT4 (FAT tumor suppressor homolog 4), also known as FAT-J, CDHF14 or CDHR11, is a 4,981 amino acid single-pass type I membrane protein that belongs to the protocadherin subfamily of cadherins and localizes to the primary cilia of kidney. Widely expressed, FAT4 contains thirty-four cadherin domains, six EGF-like domains and two laminin G-like domains. FAT4 may function in the regulation of planar cell polarity.

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