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Claudin 22 (CLDN22) (AA 101-180) Antikörper (AbBy Fluor® 555)

CLDN22 Reaktivität: Human IF (cc), IF (p) Wirt: Kaninchen Polyclonal AbBy Fluor® 555
Produktnummer ABIN2173198
  • Target Alle Claudin 22 (CLDN22) Antikörper anzeigen
    Claudin 22 (CLDN22)
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 6
    • 6
    • 1
    AA 101-180
    Reaktivität
    • 29
    • 9
    Human
    Wirt
    • 29
    Kaninchen
    Klonalität
    • 29
    Polyklonal
    Konjugat
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AbBy Fluor® 555
    Applikation
    • 15
    • 15
    • 14
    • 12
    • 12
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Claudin 22
    Isotyp
    IgG
    Top Product
    Discover our top product CLDN22 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Claudin 22 (CLDN22)
    Andere Bezeichnung
    Claudin 22 (CLDN22 Produkte)
    Synonyme
    CLDN21 antikoerper, 2210404A22Rik antikoerper, 5330431C14Rik antikoerper, 9530051B05Rik antikoerper, CLDN22 antikoerper, claudin 22 antikoerper, claudin-22 antikoerper, CLDN22 antikoerper, Cldn22 antikoerper, LOC102186369 antikoerper
    Hintergrund

    Synonyms: Claudin-22, CLD22_HUMAN, CLDN21,CLDN22, FLJ51450.

    Background: The claudin superfamily consists of many structurally related proteins that are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. It is suggested that the claudin family of proteins regulate transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specific regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-22, also known as CLDN22, is a 220 amino acid member of the claudin family that participates in tight junction-specific obliteration of the intercellular space through calcium-independent cell-adhesion activity.

    Pathways
    Cell-Cell Junction Organization, Hepatitis C
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