Claudin 23 Antikörper (AA 25-81) (AbBy Fluor® 555)

Produktnummer ABIN2173210

Produktdetails anti-Claudin 23 Antikörper (AbBy Fluor® 555)

Target: Claudin 23 (CLDN23)

Bindungsspezifität: AA 25-81

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 23 Antikörper ist konjugiert mit AbBy Fluor® 555

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Claudin 23

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Claudin 23

Target: Claudin 23 (CLDN23)

Andere Bezeichnung: Claudin 23 (CLDN23 Produkte)

Synonyme: CLDN23 antikoerper, CLDNL antikoerper, hCG1646163 antikoerper, 2310014B08Rik antikoerper, claudin 23 antikoerper, si:ch211-95j8.2 antikoerper, CLDN23 antikoerper, si:ch211-95j8.2 antikoerper, Cldn23 antikoerper

Hintergrund:

Synonyms: 2310014B08Rik, Claudin23, CLDN 23, CLDN23, CLDNL.

Background: The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-23, also known as CLDN23 or CLDNL, is a 292 amino acid multi-pass membrane protein that localizes to cell junctions and belongs to the claudin family. Expressed in stomach and placenta, as well as in germinal center B-cells, claudin-23 is thought to exhibit calcium-dependent cell-adhesion activity through which it plays an essential role in tight junction-specific obliteration of the intercellular space. Human claudin-23 shares 80 % sequence similarity with its mouse counterpart, suggesting a conserved role between species. Overexpression of claudin-23 is associated with colon tumors, implicating claudin-23 as a possible metastasis factor.

Pathways: Cell-Cell Junction Organization, Hepatitis C