CSRP2 Antikörper (AA 101-200)

Produktnummer ABIN2173630

Produktdetails anti-CSRP2 Antikörper

Target: CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))

Bindungsspezifität: AA 101-200

Reaktivität: Maus, Ratte, Huhn

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSRP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Kreuzreaktivität: Huhn, Maus, Ratte

Homologie: Human,Dog,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNM1L

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-CSRP2 Antikörper (ABIN2173630)

Hui, Lu, Han, Zhou, Liu, Li, Jin: "Resveratrol improves mitochondrial function in the remnant kidney from 5/6 nephrectomized rats." in: Acta histochemica, Vol. 119, Issue 4, pp. 392-399, (2017) (PubMed).

Ku, Ji, Zhang, Li, Sang: "PM2.5, SO2 and NO2 co-exposure impairs neurobehavior and induces mitochondrial injuries in the mouse brain." in: Chemosphere, Vol. 163, pp. 27-34, (2016) (PubMed).

Chen, Xie, Huang, Gong, Zhu, Chen, Huang, Huang: "Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-β1 via Nrf2/ARE pathway in glomerular mesangial cells." in: Free radical biology & medicine, Vol. 102, pp. 77-86, (2016) (PubMed).

Details zu CSRP2

Target: CSRP2 (Cysteine and Glycine-Rich Protein 2 (CSRP2))

Andere Bezeichnung: DLP1 (CSRP2 Produkte)

Synonyme: CRP2 antikoerper, LMO5 antikoerper, SmLIM antikoerper, crp2 antikoerper, lmo5 antikoerper, csrp1 antikoerper, smlim antikoerper, AW551867 antikoerper, Crp2 antikoerper, SmLim antikoerper, zgc:77740 antikoerper, BETA-CRP antikoerper, csrp2 antikoerper, MGC81964 antikoerper, CSRP2 antikoerper, cysteine and glycine rich protein 2 antikoerper, cysteine and glycine-rich protein 2 antikoerper, cysteine and glycine rich protein 2 L homeolog antikoerper, cysteine and glycine rich protein 2 S homeolog antikoerper, CSRP2 antikoerper, csrp2 antikoerper, Csrp2 antikoerper, csrp2.L antikoerper, csrp2.S antikoerper

Hintergrund:

Synonyms: Dynamin-1-like protein, Dnm1p/Vps1p-like protein, DVLP, Dynamin family member proline-rich carboxyl-terminal domain less, Dymple, Dynamin-like protein, Dynamin-like protein 4, Dynamin-like protein IV, HdynIV, Dynamin-related protein 1, DNM1L, DLP1, DRP1

Background: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis, this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution. Isoform 1 and isoform 4 inhibit peroxisomal division when overexpressed.

Gen-ID: 10059

UniProt: O00429