GADD34 Antikörper (AA 401-500) (AbBy Fluor® 488)
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- Target Alle GADD34 (PPP1R15A) Antikörper anzeigen
- GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
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Bindungsspezifität
- AA 401-500
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GADD34 Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GADD34
- Isotyp
- IgG
- Top Product
- Discover our top product PPP1R15A Primärantikörper
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- Applikationshinweise
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- GADD34 (PPP1R15A) (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A (PPP1R15A))
- Andere Bezeichnung
- GADD34 (PPP1R15A Produkte)
- Synonyme
- 9630030H21 antikoerper, Gadd34 antikoerper, Myd116 antikoerper, GADD34 antikoerper, Peg-3 antikoerper, RGD1624209 antikoerper, protein phosphatase 1 regulatory subunit 15A antikoerper, protein phosphatase 1, regulatory (inhibitor) subunit 15A antikoerper, protein phosphatase 1, regulatory subunit 15A antikoerper, PPP1R15A antikoerper, Ppp1r15a antikoerper
- Hintergrund
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Synonyms: GADD34, Protein phosphatase 1 regulatory subunit 15A, Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, PPP1R15A
Background: Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
- Gen-ID
- 23645
- UniProt
- O75807
- Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
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