GPR37L1 Antikörper (AA 101-200)

Produktnummer ABIN2174801

Produktdetails anti-GPR37L1 Antikörper

Target: GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))

Bindungsspezifität: AA 101-200

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR37L1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR37L1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu GPR37L1

Target: GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))

Andere Bezeichnung: GPR37L1 (GPR37L1 Produkte)

Synonyme: GPR37L1 antikoerper, ET(B)R-LP-2 antikoerper, ETBR-LP-2 antikoerper, AW047233 antikoerper, CAG-18 antikoerper, D0Kist8 antikoerper, G protein-coupled receptor 37 like 1 antikoerper, G protein-coupled receptor 37-like 1 antikoerper, GPR37L1 antikoerper, Gpr37l1 antikoerper

Hintergrund:

Synonyms: Endothelin B receptor-like protein 2, ET(B)R-LP-2, ETBR-LP-2, ETBR2, ETBRLP2, G-protein coupled receptor 37-like 1, GPR37L1, ETBR2_HUMAN.

Background: G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.

Gen-ID: 9283

UniProt: O60883