GPR37L1 Antikörper (AA 101-200) (AbBy Fluor® 488)
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- Target Alle GPR37L1 Antikörper anzeigen
- GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))
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Bindungsspezifität
- AA 101-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GPR37L1 Antikörper ist konjugiert mit AbBy Fluor® 488
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Applikation
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Homologie
- Human,Mouse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GPR37L1
- Isotyp
- IgG
- Top Product
- Discover our top product GPR37L1 Primärantikörper
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- Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))
- Andere Bezeichnung
- Gpr37l1 (GPR37L1 Produkte)
- Synonyme
- GPR37L1 antikoerper, ET(B)R-LP-2 antikoerper, ETBR-LP-2 antikoerper, AW047233 antikoerper, CAG-18 antikoerper, D0Kist8 antikoerper, G protein-coupled receptor 37 like 1 antikoerper, G protein-coupled receptor 37-like 1 antikoerper, GPR37L1 antikoerper, Gpr37l1 antikoerper
- Hintergrund
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Synonyms: Endothelin B receptor-like protein 2, ET(B)R-LP-2, ETBR-LP-2, ETBR2, ETBRLP2, G-protein coupled receptor 37-like 1, GPR37L1, ETBR2_HUMAN.
Background: G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.
- Gen-ID
- 9283
- UniProt
- O60883
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