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Hepcidin 25 Antikörper (AA 60-84) (AbBy Fluor® 350)

HEPC25 Reaktivität: Human IF (p), WB, IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 350
Produktnummer ABIN2175580
  • Target Alle Hepcidin 25 (HEPC25) Antikörper anzeigen
    Hepcidin 25 (HEPC25)
    Bindungsspezifität
    • 29
    • 1
    • 1
    AA 60-84
    Reaktivität
    • 16
    • 15
    • 15
    Human
    Wirt
    • 31
    Kaninchen
    Klonalität
    • 31
    Polyklonal
    Konjugat
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Hepcidin 25 Antikörper ist konjugiert mit AbBy Fluor® 350
    Applikation
    • 25
    • 16
    • 12
    • 6
    • 5
    • 3
    • 1
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Hepcidin 25
    Isotyp
    IgG
    Top Product
    Discover our top product HEPC25 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Hepcidin 25 (HEPC25)
    Andere Bezeichnung
    Hepcidin 25 (HEPC25 Produkte)
    Synonyme
    HEPC antikoerper, HFE2B antikoerper, LEAP1 antikoerper, PLTR antikoerper, hepcidin antimicrobial peptide antikoerper, HAMP antikoerper
    Hintergrund

    Synonyms: Hamp, HEPC, HEPC_HUMAN, Hepc20, Hepc25, HEPCIDIN, Hepcidin, Hepcidin 20, Hepcidin 25, Hepcidin antimicrobial peptide, Hepcidin-20, Hepcidin25, HFE2, HFE2B, LEAP 1, LEAP-1, LEAP1, Liver expressed antimicrobial peptide, Liver-expressed antimicrobial peptide 1, PLTR, Putative liver tumor regressor.

    Background: The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure. [provided by RefSeq, Jul 2008].

    Gen-ID
    57817
    UniProt
    P81172
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