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IRF9 Antikörper (AA 101-200) (Biotin)

IRF9 Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN2177070
  • Target Alle IRF9 Antikörper anzeigen
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Bindungsspezifität
    • 14
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-200
    Reaktivität
    • 47
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 41
    • 7
    • 1
    Kaninchen
    Klonalität
    • 43
    • 5
    Polyklonal
    Konjugat
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser IRF9 Antikörper ist konjugiert mit Biotin
    Applikation
    • 35
    • 14
    • 13
    • 13
    • 10
    • 9
    • 6
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IRF9
    Isotyp
    IgG
    Top Product
    Discover our top product IRF9 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Andere Bezeichnung
    IRF9 (IRF9 Produkte)
    Synonyme
    IRF-9 antikoerper, ISGF3 antikoerper, ISGF3G antikoerper, p48 antikoerper, zgc:92097 antikoerper, Irf-9 antikoerper, Isgf3g antikoerper, interferon regulatory factor 9 antikoerper, IRF9 antikoerper, irf9 antikoerper, Irf9 antikoerper
    Hintergrund

    Synonyms: p48, IRF-9, ISGF3, ISGF3G, Interferon regulatory factor 9, IFN-alpha-responsive transcription factor subunit, ISGF3 p48 subunit, Interferon-stimulated gene factor 3 gamma, ISGF-3 gamma, Transcriptional regulator ISGF3 subunit gamma, IRF9

    Background: Transcription factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

    Gen-ID
    10379
    UniProt
    Q00978
    Pathways
    JAK-STAT Signalweg, Interferon-gamma Pathway, Hepatitis C
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