PCDHB14 Antikörper (AA 551-650) (AbBy Fluor® 488)

Produktnummer ABIN2178270

Produktdetails anti-PCDHB14 Antikörper (AbBy Fluor® 488)

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Bindungsspezifität: AA 551-650

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PCDHB14 Antikörper ist konjugiert mit AbBy Fluor® 488

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Sheep

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PCDHB14

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PCDHB14

Target: PCDHB14 (Protocadherin beta 14 (PCDHB14))

Andere Bezeichnung: Pcdhb14 (PCDHB14 Produkte)

Synonyme: PCDH-BETA14 antikoerper, 2210006M07Rik antikoerper, Pcdhb17 antikoerper, PcdhbN antikoerper, PCDHB14 antikoerper, protocadherin beta 14 antikoerper, protocadherin beta-14 antikoerper, PCDHB14 antikoerper, Pcdhb14 antikoerper, LOC487175 antikoerper, LOC100061546 antikoerper, LOC100353156 antikoerper

Hintergrund:

Synonyms: MGC120065, PCDBE_HUMAN, PCDH beta14, PCDH-beta-14, PCDHB 14, PCDHB14, Protocadherin beta 14, Protocadherin beta-14.

Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB14 (Protocadherin beta 14) is a 798 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whos genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB14) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB14 is a single-pass type I membrane protein that contains six cadherin domains.