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PCDHB6 Antikörper (AA 21-120) (AbBy Fluor® 555)

PCDHB6 Reaktivität: Human IF (p), IF (cc) Wirt: Kaninchen Polyclonal AbBy Fluor® 555
Produktnummer ABIN2178283
  • Target Alle PCDHB6 Produkte
    PCDHB6 (Protocadherin beta 6 (PCDHB6))
    Bindungsspezifität
    • 14
    • 1
    • 1
    AA 21-120
    Reaktivität
    Human
    Wirt
    • 14
    • 3
    Kaninchen
    Klonalität
    • 15
    • 2
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PCDHB6 Antikörper ist konjugiert mit AbBy Fluor® 555
    Applikation
    • 12
    • 12
    • 5
    • 3
    • 3
    • 3
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PCDHB6
    Isotyp
    IgG
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    PCDHB6 (Protocadherin beta 6 (PCDHB6))
    Andere Bezeichnung
    Pcdhb6 (PCDHB6 Produkte)
    Synonyme
    PCDH-BETA6 antikoerper, Pcdhb5B antikoerper, PcdhbF antikoerper, protocadherin beta 6 antikoerper, PCDHB6 antikoerper, Pcdhb6 antikoerper
    Hintergrund

    Synonyms: PCDH beta6,,PCDH beta 6, PCDHB 6, Protocadherin beta 6.

    Background: Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB6 (Protocadherin beta-6) is a 794 amino acid single pass transmembrane protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB6) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. PCDHB6 is likely a calcium-dependent cell adhesion protein that is involved in the maintenance of neural connections in the brain. Unlike most protocadherin-beta proteins, PCDHB6 has not one but two PXXP motifs within its cytoplasmic domain, suggesting a role in signal transduction cascade events.

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