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SLK Antikörper (AA 165-270) (Biotin)

SLK Reaktivität: Human, Maus WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal Biotin
Produktnummer ABIN2179268
  • Target Alle SLK Antikörper anzeigen
    SLK (STE20-Like Kinase (SLK))
    Bindungsspezifität
    • 15
    • 15
    • 14
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 165-270
    Reaktivität
    • 51
    • 41
    • 26
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 65
    • 1
    Kaninchen
    Klonalität
    • 65
    • 1
    Polyklonal
    Konjugat
    • 18
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SLK Antikörper ist konjugiert mit Biotin
    Applikation
    • 42
    • 39
    • 39
    • 14
    • 10
    • 8
    • 7
    • 7
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Human, Maus
    Homologie
    Rat,Dog,Cow,Pig,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SLK
    Isotyp
    IgG
    Top Product
    Discover our top product SLK Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    SLK (STE20-Like Kinase (SLK))
    Andere Bezeichnung
    SLK (SLK Produkte)
    Synonyme
    BcDNA:LD05623 antikoerper, CG40293 antikoerper, Dmel\\CG40293 antikoerper, LD05623 antikoerper, LOSK antikoerper, STK2 antikoerper, bA16H23.1 antikoerper, se20-9 antikoerper, 9A2 antikoerper, AV021402 antikoerper, AW411554 antikoerper, Etk4 antikoerper, SMAK antikoerper, Stk2 antikoerper, mKIAA0204 antikoerper, mSLK antikoerper, STE20 like kinase antikoerper, Ste20-like kinase antikoerper, STE20-like kinase antikoerper, SLK antikoerper, Stlk antikoerper, Slk antikoerper
    Hintergrund

    Synonyms: Fyn, C syn protooncogene, FYN oncogene related to SRC FGR YES_ MGC45350, OKT3 induced calcium influx regulator, P59 FYN, Protein tyrosine kinase fyn, Proto oncogene tyrosine protein kinase fyn, Protooncogene Syn, SLK, Src like kinase, Src yes related novel gene, Src/yes related novel gene,SYN, Tyrosine kinase p59fyn T, Tyrosine kinase p59fynT.

    Background: Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59 kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1.The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR. Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of Fyn activity. Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.

    Gen-ID
    9748
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