TAB3 Antikörper (PE)

Produktnummer ABIN2179514

Produktdetails anti-TAB3 Antikörper (PE)

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAB3 Antikörper ist konjugiert mit PE

Applikation: Western Blotting (WB)

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TAB3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Details zu TAB3

Target: TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))

Andere Bezeichnung: Tab3 (TAB3 Produkte)

Synonyme: MAP3K7IP3 antikoerper, NAP1 antikoerper, 4921526G09Rik antikoerper, Map3k7ip3 antikoerper, mKIAA4135 antikoerper, map3k7ip3 antikoerper, nap1 antikoerper, tab3 antikoerper, tab3-a antikoerper, tab3-b antikoerper, map3k7ip3l antikoerper, si:ch211-232d19.8 antikoerper, si:dkey-30h22.6 antikoerper, TGF-beta activated kinase 1 and MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog antikoerper, TAB3 antikoerper, Tab3 antikoerper, tab3.S antikoerper, tab3 antikoerper

Hintergrund:

Synonyms: MAP3K7IP 3, Mitogen activated protein kinase kinase kinase 7 interacting protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NAP1, NF kappa B activating protein 1, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, TAB3, TAB3_HUMAN, TAK1 binding protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1-binding protein 3.

Background: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

Gen-ID: 257397

UniProt: Q8N5C8

Pathways: TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades