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TAB3 Antikörper (PE)

TAB3 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal PE
Produktnummer ABIN2179514
  • Target Alle TAB3 Antikörper anzeigen
    TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
    Reaktivität
    • 40
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 39
    • 1
    Kaninchen
    Klonalität
    • 39
    • 1
    Polyklonal
    Konjugat
    • 19
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TAB3 Antikörper ist konjugiert mit PE
    Applikation
    • 24
    • 21
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TAB3
    Isotyp
    IgG
    Top Product
    Discover our top product TAB3 Primärantikörper
  • Applikationshinweise
    FCM: (1:20-100)
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
  • Target
    TAB3 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 3 (TAB3))
    Andere Bezeichnung
    Tab3 (TAB3 Produkte)
    Synonyme
    MAP3K7IP3 antikoerper, NAP1 antikoerper, 4921526G09Rik antikoerper, Map3k7ip3 antikoerper, mKIAA4135 antikoerper, map3k7ip3 antikoerper, nap1 antikoerper, tab3 antikoerper, tab3-a antikoerper, tab3-b antikoerper, map3k7ip3l antikoerper, si:ch211-232d19.8 antikoerper, si:dkey-30h22.6 antikoerper, TGF-beta activated kinase 1 and MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 antikoerper, TGF-beta activated kinase 1/MAP3K7 binding protein 3 S homeolog antikoerper, TAB3 antikoerper, Tab3 antikoerper, tab3.S antikoerper, tab3 antikoerper
    Hintergrund

    Synonyms: MAP3K7IP 3, Mitogen activated protein kinase kinase kinase 7 interacting protein 3, Mitogen-activated protein kinase kinase kinase 7-interacting protein 3, NAP1, NF kappa B activating protein 1, NF-kappa-B-activating protein 1, NFkB activating protein 1, TAB-3, TAB3, TAB3_HUMAN, TAK1 binding protein 3, TAK1-binding protein 3, TGF-beta-activated kinase 1 and MAP3K7-binding protein 3, TGF-beta-activated kinase 1-binding protein 3.

    Background: The product of this gene functions in the NF-kappaB signal transduction pathway. The encoded protein, and the similar and functionally redundant protein MAP3K7IP2/TAB2, forms a ternary complex with the protein kinase MAP3K7/TAK1 and either TRAF2 or TRAF6 in response to stimulation with the pro-inflammatory cytokines TNF or IL-1. Subsequent MAP3K7/TAK1 kinase activity triggers a signaling cascade leading to activation of the NF-kappaB transcription factor. The human genome contains a related pseudogene. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

    Gen-ID
    257397
    UniProt
    Q8N5C8
    Pathways
    TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades
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