FERMT3 Antikörper (AA 401-500) (Biotin)

Produktnummer ABIN2179987

Produktdetails anti-FERMT3 Antikörper (Biotin)

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Bindungsspezifität: AA 401-500

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FERMT3 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human URP2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu FERMT3

Target: FERMT3 (Fermitin Family Member 3 (FERMT3))

Andere Bezeichnung: URP2 (FERMT3 Produkte)

Hintergrund:

Synonyms: Fermitin family homolog 3, Fermitin family member 3, FERMT3, Kind3, Kindlin 3, Kindlin-3, Kindlin3, MGC10966, MIG 2, MIG2 like protein, MIG2-like protein, MIG2B, Unc 112 related protein 2, Unc-112-related protein 2, UNC112C, URP2_HUMAN, URP2SF.

Background: Kindlin-3 is a 667 amino acid protein that localizes to both the cell membrane and the cytoplasm and contains one PH domain and one FERM domain. Expressed at high levels in lymph node tissue and at lower levels in spleen, thymus, stomach, placenta, lung, testis and small intestine, Kindlin-3 is thought to be involved in cell adhesion events and may play a role in apoptosis. Kindlin-3 is overexpressed in B-cell malignancies, suggesting that, via its ability to affect cell adhesion, Kindlin-3 may participate in tumor transformation and metastasis. Two isforms of Kindlin-3, designated short and long, exist due to alternative splicing events.