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TNF alpha Antikörper
TNF alpha
Reaktivität: Human
WB, FACS, IP, IA
Wirt: Maus
Monoclonal
T 3
unconjugated
Produktnummer ABIN2191893
Produktdetails anti-TNF alpha Antikörper
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Target
Alle TNF alpha Antikörper anzeigen
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Reaktivität
Alle Reaktivitäten für TNF alpha Antikörper
Human
Wirt
Alle Wirte für TNF alpha Antikörper
Maus
Klonalität
Alle Klonalitäten für TNF alpha Antikörper
Monoklonal
Konjugat
Alle Konjugate für TNF alpha Antikörper
Dieser TNF alpha Antikörper ist unkonjugiert
Applikation
Alle Applikationen für TNF alpha Antikörper
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunoassay (IA)
Sterilität
0.2 μm filtered
Klon
T 3
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Anwendungsinformationen
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Applikationshinweise
For flow cytometry and Western blotting dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Buffer
PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
Haltbarkeit
12 months
Referenzen für anti-TNF alpha Antikörper (ABIN2191893)
(ausblenden)
Gerspach, Götz, Zimmermann, Kolle, Böttinger, Grell : "Detection of membrane-bound tumor necrosis factor (TNF): an analysis of TNF-specific reagents. " in: Microscopy research and technique , Vol. 50 , Issue 3 , pp. 243-50 , (2000 ) (PubMed ).
Details zu TNF alpha
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Target
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Andere Bezeichnung
Tumor Necrosis Factor alpha (TNF alpha Produkte )
Synonyme
DIF antikoerper, TNF-alpha antikoerper, TNFA antikoerper, TNFSF2 antikoerper, RATTNF antikoerper, Tnfa antikoerper, tnf antikoerper, TNF-a antikoerper, TNFalpha antikoerper, Tnfsf1a antikoerper, TNFa antikoerper, cTNF antikoerper, Tnf-alpha antikoerper, tnfa-like antikoerper, TNF-ALPHA antikoerper, dif antikoerper, tnfa antikoerper, xtnf antikoerper, tnfsf2 antikoerper, tnf-alpha antikoerper, Cachectin antikoerper, tumor necrosis factor antikoerper, tumor necrosis factor b (TNF superfamily, member 2) antikoerper, tumor necrosis factor alpha antikoerper, tumor necrosis factor a (TNF superfamily, member 2) antikoerper, TNF antikoerper, Tnf antikoerper, tnf antikoerper, tnfb antikoerper, tnf-alpha antikoerper, LOC103694380 antikoerper, tnfa antikoerper
Hintergrund
The antibody reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-alpha. The antibody inhibits the biological activity of soluble and membrane TNF-alpha. The antibody can be a useful tool to discriminate between receptor bound soluble (17 kDa) and the membrane (26 kDa) form of TNF-alpha. For this purpose we recommend to use this antibody in combination with the anti-TNF-alpha antibody HM2024, which recognizes only soluble and membrane TNF-alpha, but not the receptor bound TNF-alpha.
Pathways
NF-kappaB Signalweg , Apoptose , Caspase Kaskade in der Apoptose , TLR Signalweg , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
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