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MYO1G Antikörper (C-Term)

Rockland 600-401-959 MYO1G Reaktivität: Human WB, ELISA, IP Wirt: Kaninchen Polyclonal unconjugated
Rockland
Produktnummer ABIN233814
Hersteller Produkt- Nr.: 600-401-959
  • Target Alle MYO1G Antikörper anzeigen
    MYO1G (Myosin IG (MYO1G))
    Bindungsspezifität
    • 5
    • 2
    • 1
    C-Term
    Reaktivität
    • 8
    • 1
    Human
    Wirt
    • 9
    Kaninchen
    Klonalität
    • 9
    Polyklonal
    Konjugat
    • 3
    • 3
    • 2
    • 1
    Dieser MYO1G Antikörper ist unkonjugiert
    Applikation
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunoprecipitation (IP)
    Hersteller Produkt- Nr.
    600-401-959
    Hersteller
    Rockland
    Verwendungszweck
    Myosin 1G Antibody
    Kreuzreaktivität (Details)
    This affinity-purified antibody is directed against human Myosin 1G protein.
    Produktmerkmale
    Synonyms: rabbit anti-Myosin 1G antibody, Unconventional myosin-Ig, Minor histocompatibility antigen HA-2, mHag HA-2, MYO1G
    Aufreinigung
    The product was affinity purified from monospecific antiserum by immunoaffinity purification.
    Sterilität
    Sterile filtered
    Immunogen

    Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-terminal region of human Myosin 1G protein.

    Immunogen Type: Conjugated Peptide

    Isotyp
    IgG
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  • Applikationshinweise

    Application Note: This affinity-purified antibody has been tested for use in ELISA, western blotting and possibly in immunoprecipitation as well.  Specific conditions for reactivity should be optimized by the end user. By western blot a band approximately 100 kDa in size corresponding to Myosin 1G protein is expected in the appropriate cell lysate or extract.

    Western Blot Dilution: 1:500 - 1:3,000

    Immunoprecipitation Dilution: 1:100

    ELISA Dilution: 1:10,000 - 1:40,000

    Other: User Optimized

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1.2 mg/mL
    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
    Haltbarkeit
    12 months
  • Olety, Wälte, Honnert, Schillers, Bähler: "Myosin 1G (Myo1G) is a haematopoietic specific myosin that localises to the plasma membrane and regulates cell elasticity." in: FEBS letters, Vol. 584, Issue 3, pp. 493-9, (2010) (PubMed).

  • Target
    MYO1G (Myosin IG (MYO1G))
    Andere Bezeichnung
    MYO1G (MYO1G Produkte)
    Hintergrund
    Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. In general, myosins are protein complexes consisting of one or more myosin heavy chains, associated light chains and other proteins.  Myosins function as molecular motors and use the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments.  Myosins have magnesium-ATPase activity and bind actin. Myosins can be divided into classes that are distinguished based on sequence features of the motor, or head domain, but also have distinct tail regions that are believed to bind specific cargoes. Unconventional myosins exist.  Myosin 1G is an unconventional myosin that is restricted to hematopoietic cells. Unconventional myosins are also critical for motility in amoeba and a mammalian paralog (Myo1C) is critical as a glucose transporter that recycles glucose in response to insulin.
    Gen-ID
    64005, 239582755
    UniProt
    B0I1T2
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