Prekallikrein Antikörper (Heavy Chain)

Produktnummer ABIN236108

Produktdetails anti-Prekallikrein Antikörper

Target: Prekallikrein (PK)

Bindungsspezifität: Heavy Chain

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Prekallikrein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: Recognizes two variants (88 kDa and 85 kDa) of prekallikrein and its activation products kallikrein (88 kDa and 85 kDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45 kDa prekallikrein/kallikrein fragment(s). Recognizes prekallikrein and its activation products in human, chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.

Produktmerkmale: MAb to Prekallikrein Heavy Chain, Monoclonal antibody to Prekallikrein Heavy Chain

Aufreinigung: Protein G Chromatography. Ascites

Immunogen: Purified human plasma prekallikrein

Klon: 901

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Suitable for use in ELISA and Western blot. Note: Prekallikrein activation may occur with repeated freezing/thawing (3x or more) of plasma samples. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS, pH 7.4.

Konservierungsmittel: Without preservative

Handhabung: Avoid multiple freeze/thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, aliquot and store at -20 °C.

Details zu Prekallikrein

Target: Prekallikrein (PK)

Andere Bezeichnung: Prekallikrein (PK Produkte)

Synonyme: APS antikoerper, KLK2A1 antikoerper, PSA antikoerper, hK3 antikoerper, kallikrein related peptidase 3 antikoerper, KLK3 antikoerper