CEACAM20 Antikörper

Produktnummer ABIN238330

Produktdetails anti-CEACAM20 Antikörper

Target: CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CEACAM20 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Cell-ELISA (cELISA)

Aufreinigung: Protein G

Immunogen: genetic immunisation with cDNA encoding human CEACAM20

Klon: HT-12D8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS, pH 7.2

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C

Informationen zur Lagerung: short term: 2 °C - 8 °C, long term: -20 °C

Details zu CEACAM20

Target: CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))

Andere Bezeichnung: CEACAM20 (CEACAM20 Produkte)

Synonyme: UNQ9366 antikoerper, 9130012D09Rik antikoerper, carcinoembryonic antigen related cell adhesion molecule 20 antikoerper, carcinoembryonic antigen-related cell adhesion molecule 20 antikoerper, CEACAM20 antikoerper, Ceacam20 antikoerper

Hintergrund: CEA-related cell adhesion molecule 20 (CEACAM20) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a putative glycoprotein which is membrane-bound via a transmembrane domain. The CEACAM20 protein contains a single N domain followed by 4 immunoglobulin-like A (A1, A2) and B (B1, B2) domains. Expression of CEACAM20 can be found in tissues of prostate, testis, duodenum and small intestine with highest expression in prostate. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. High expression of CEACAM20 in tissue of prostate carcinoma and in prostate carcinoma cell lines suggest that CEACAM20 can be used as a tumor marker.

UniProt: Q6UY09