Mycobacterium Tuberculosis Antigen CFP10 (Rv3874) Antikörper

Produktnummer ABIN238347

Produktdetails

Target: Mycobacterium Tuberculosis Antigen CFP10 (Rv3874)

Reaktivität: Mycobacterium tuberculosis

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The polyclonal antibody reacts with CFP10 (LHP), a 12,3 kDa antigen encoded by gene Rv3874 of Mycobacterium tuberculosis. The antibody recognizes CFP10 of Mycobacterium tuberculosis H37Rv and Mycobacterium bovis, it reacts also with recombinant antigen produced in Escherichia coli.

Aufreinigung: Protein-A affinity chromatography.

Immunogen: CFP10 (Rv3874) of Mycobacterium tuberculosis

Anwendungsinformationen

Applikationshinweise: Suitable for Western Blotting under Reducing conditions: 0.2-1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 with 15 mM sodium azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Antigendetails

Target: Mycobacterium Tuberculosis Antigen CFP10 (Rv3874)

Andere Bezeichnung: Cfp10 / EsxB

Substanzklasse: Bacteria

Hintergrund: CFP10 (10 kDa culture filtrate protein) is a low molecular weight protein isolated from Mycobacterium tuberculosis culture filtrates. CFP10 and the 6 kDa early secretory antigen of T cells (ESAT6) are secreted in abundance by Mycobacterium tuberculosis and are frequently recognized by T cells from infected people. The genes encoding these proteins have been deleted from the genome of the vaccine strain Bacille Calmette Guerin (BCG). CFP10 is one of a small number of secreted M. tuberculosis proteins now identified, that appear to play key roles in tuberculosis pathogenesis and in the stimulation of immunity.Synonyms: 10 kDa culture filtrate antigen cfp10, ESAT-6-like protein esxB, MT3988, MTV027.09, Rv3874, Secreted antigenic protein MTSA-10, lhp, mtsA10

Gen-ID: 886194

NCBI Accession: NP_218391

UniProt: P0A566