CD4 Antikörper

Produktnummer ABIN238364

Produktdetails anti-CD4 Antikörper

Target: CD4

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD4 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)

Spezifität: The CD4 antigen is a monomeric transmembrane glycoprotein with a molecular weight (Mr) of 60 kDa. CD4 Molecule is expressed on a specific subset of peripheral blood T lymphocytes named ''helper/inducer''. The CD4 antige is present on approximately 45 % of peripheral blood lymphocytes (T4 lymphocytes), 80 % of thymocytes and with a lower density of 100 % of monocytes and on some neutrophils.

Produktmerkmale: Synonyms: T4/Leu-3, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

Immunogen: Human thymocytes

Klon: 13B8-2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow cytometry: Studies of CD4 expressing cells. Fluorescence microscopy or Flow cytometry: 2 g/5x10e5 cells/test. Immunohistochemistry: Working dilution 1/25-1/50. Only suitable on cryostat sections or cell smears.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: Reconstitute with 1 mL distilled water.

Konzentration: 0.2 mg/mL (prior to lyophilization)

Buffer: PBS containing 1 mg/mL BSA as stabilizer without preservatives.

Konservierungsmittel: Without preservative

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store lyophilized (preferably in a desiccator) at 2-8 °C and reconstituted (in aliquots) at-20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CD4

Target: CD4

Andere Bezeichnung: CD4 (CD4 Produkte)

Synonyme: cd4 antikoerper, L3T4 antikoerper, Ly-4 antikoerper, CD4mut antikoerper, W3/25 antikoerper, p55 antikoerper, CD4 molecule antikoerper, carcinoembryonic antigen-related cell adhesion molecule 5 antikoerper, T-cell surface glycoprotein CD4 antikoerper, CD4 antigen antikoerper, Cd4 molecule antikoerper, CD4 antikoerper, LOC100125525 antikoerper, cd4 antikoerper, Cd4 antikoerper

Hintergrund: CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4

Gen-ID: 920

UniProt: P01730

Pathways: T-Zell Rezeptor Signalweg, Maintenance of Protein Location, CXCR4-mediated Signaling Events