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Transferrin Receptor Antikörper (PE)

TFRC Reaktivität: Human FACS Wirt: Maus Monoclonal MEM-75 PE
Produktnummer ABIN238476
  • Target Alle Transferrin Receptor (TFRC) Antikörper anzeigen
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Reaktivität
    • 203
    • 89
    • 33
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 122
    • 111
    • 35
    • 1
    • 1
    Maus
    Klonalität
    • 172
    • 94
    • 3
    Monoklonal
    Konjugat
    • 124
    • 27
    • 23
    • 16
    • 10
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Transferrin Receptor Antikörper ist konjugiert mit PE
    Applikation
    • 161
    • 135
    • 70
    • 66
    • 60
    • 42
    • 26
    • 25
    • 20
    • 12
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Aufreinigung
    Size-exclusion chromatography.
    Immunogen
    NALM-6 human pre-B cell line
    Klon
    MEM-75
    Isotyp
    IgG1
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  • Applikationshinweise
    Further Comments: This antibody is designed for Flow Cytometry analysis of human blood cells using 20 m l reagent/100 m l of whole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 15 mM sodium azide as preservative and 0.2 % (w/v) high-grade BSA (Protease free) as stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    Store the antibody in the dark at 2-8 °C. Do Not Freeze! Avoid prolonged exposure to light.
    Shelf Life: one year from despatch.
    Haltbarkeit
    12 months
  • Target
    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))
    Andere Bezeichnung
    CD71 / TFRC (TFRC Produkte)
    Hintergrund
    CD71 (transferrin receptor) is a type II transmembrane glycoprotein expressed as homodimer in erythroid blood cell line and in activated leukocytes. Upon binding of holotransferrin (complex of transferrin and iron ions), CD71 is internalized by clathrin-mediated endocytosis. Acidification of endosomes by vesicular membrane proton pumps leads to dissociation of iron ions, whereas transferrin (apotransferrin) remains associated with CD71 and recycles to the cell surface, where it is released upon exposure to normal pH . CD71 is also involved in uptake of non-transferrin bound iron.Synonyms: TfR1, Transferrin receptor protein 1, p90
    UniProt
    P02786
    Pathways
    Transition Metal Ion Homeostasis
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