×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
CDK4 Antikörper
CDK4
Reaktivität: Human, Maus, Ratte
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN2427935
Produktdetails anti-CDK4 Antikörper
(ausblenden)
Target
Alle CDK4 Antikörper anzeigen
CDK4
(Cyclin-Dependent Kinase 4 (CDK4))
Reaktivität
Alle Reaktivitäten für CDK4 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für CDK4 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für CDK4 Antikörper
Polyklonal
Konjugat
Alle Konjugate für CDK4 Antikörper
Dieser CDK4 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CDK4 Antikörper
Western Blotting (WB), ELISA
Aufreinigung
Affinity purification
Immunogen
Recombinant protein of human CDK4
Isotyp
IgG
Top Product
Discover our top product CDK4 Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
WB 1:500-1:2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Format
Liquid
Konzentration
0.4 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Konservierungsmittel
Sodium azide
Handhabung
Avoid freeze / thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Referenzen für anti-CDK4 Antikörper (ABIN2427935)
(ausblenden)
Li, Meng, Hao, Tao, Zou, Li, Ming, Ding, Dong, Feng, Li, Wang, Wu : "Immune regulation mechanism of Astragaloside IV on RAW264.7 cells through activating the NF-κB/MAPK signaling pathway. " in: International immunopharmacology , Vol. 49 , pp. 38-49 , (2018 ) (PubMed ).
Details zu CDK4
(ausblenden)
Target
CDK4
(Cyclin-Dependent Kinase 4 (CDK4))
Andere Bezeichnung
CDK4 (CDK4 Produkte )
Synonyme
zgc:153726 antikoerper, CMM3 antikoerper, PSK-J3 antikoerper, Crk3 antikoerper, 8-6 antikoerper, CDK4 antikoerper, CDK4/6 antikoerper, CG5072 antikoerper, Cdk4/6 antikoerper, DmCdk4 antikoerper, Dmel\\CG5072 antikoerper, Pk53C antikoerper, Pk?7 antikoerper, cdk antikoerper, cdk4 antikoerper, cdk4/6 antikoerper, dCdk4 antikoerper, l(2)05428 antikoerper, l(2)0671 antikoerper, l(2)k06503 antikoerper, l(2)s4639 antikoerper, l(2)sh0671 antikoerper, xcdk4 antikoerper, cyclin-dependent kinase 4 antikoerper, cyclin dependent kinase 4 antikoerper, Cyclin-dependent kinase 4 antikoerper, cyclin-dependent kinase 4 L homeolog antikoerper, cdk4 antikoerper, CDK4 antikoerper, Cdk4 antikoerper, cdk4.L antikoerper
Hintergrund
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported.
Molekulargewicht
Calculated MW: 34 kDa
Pathways
Zellzyklus , Mitotic G1-G1/S Phases , Regulation of Cell Size
Zuletzt angesehen
(ausblenden)